The study concerns new syntheses of 5-hydroxy ether and 5-aminohydroxy ether derivatives of pyrimidine. When tested for antibacterial activity, some of the compounds exhibited promising effects.

Synthesis and Biological Investigations of Pyrimidine Derivatives. -Among the newly synthesized pyrimidines (III), (V), and (VII) the epoxy derivative (IIIb) shows good activity against Staphylococcus epidermis, while (VII) is active against Escherichia coli. -(CIEPLIK, J.; PLUTA, J.; MELER, G.; Arch.