Biological systems can generate microstructured materials that combine organic and inorganic components and possess diverse physical and chemical properties. However, these natural processes in materials fabrication are not readily programmable. Here, we use a synthetic-biology approach to mimic such natural processes to assemble patterned materials.. We demonstrate programmable fabrication of three-dimensional (3D) materials by printing engineered self-patterning bacteria on permeable membranes that serve as a structural scaffold. Application of gold nanoparticles to the colonies creates hybrid organic-inorganic dome structures. The dynamics of the dome structures' response to pressure is determined by their geometry (colony size, dome height and pattern), which is easily modified by varying the properties of the membrane (e.g., pore size and hydrophobicity). We generate resettable pressure sensors that process signals in response to varying pressure intensity and duration.

The Scallop theorem states that reciprocal methods of locomotion, such as jet propulsion or paddling, will not work in Stokes flow (Reynolds number=0). In nature the effective limit of jet propulsion is still in the range where inertial forces are significant. It appears that almost all animals that use jet propulsion swim at Reynolds numbers (Re) of about 5 or more. Juvenile squid and octopods hatch from the egg already swimming in this inertial regime. Juvenile jellyfish, or ephyrae, break off from polyps swimming at Re greater than 5. Many other organisms, such as scallops, rarely swim at Re less than 100. The limitations of jet propulsion at intermediate Re is explored here using the immersed boundary method to solve the 2D Navier-Stokes equations coupled to the motion of a simplified jellyfish. The contraction and expansion kinematics are prescribed, but the forward and backward swimming motions of the idealized jellyfish are emergent properties determined by the resulting fluid dynamics. Simulations are performed for both an oblate bell shape using a paddling mode of swimming and a prolate bell shape using jet propulsion. Average forward velocities and work put into the system are calculated for Re between 1 and 320. The results show that forward velocities rapidly decay with decreasing Re for all bell shapes when Re<10. Similarly, the work required to generate the pulsing motion increases significantly for Re<10. When compared to actual organisms, the swimming velocities and vortex separation patterns for the model prolate agree with those observed in Nemopsis bachei. The forward swimming velocities of the model oblate jellyfish after two pulse cycles are comparable to those reported for Aurelia aurita, but discrepancies are observed in the vortex dynamics between when the 2D model oblate jellyfish and the organism. This discrepancy is likely due to a combination of the differences between the 3D reality of the jellyfish and the 2D simplification, as well as the rigidity of the time varying geometry imposed by the idealized model.

By comparing a specific redistricting plan to an ensemble of plans, we evaluate whether the plan translates individual votes to election outcomes in an unbiased fashion. Explicitly, we evaluate if a given redistricting plan exhibits extreme statistical properties compared to an ensemble of nonpartisan plans satisfying all legal criteria. Thus, we capture how unbiased redistricting plans interpret individual votes via a state's geopolitical landscape. We generate the ensemble of plans through a Markov chain Monte Carlo algorithm coupled with simulated annealing based on a reference distribution that does not include partisan criteria. Using the ensemble and historical voting data, we create a null hypothesis for various election results, free from partisanship, accounting for the state's geo-politics. We showcase our methods on two recent congressional districting plans of NC, along with a plan drawn by a bipartisan panel of retired judges. We find the enacted plans are extreme outliers whereas the bipartisan judges' plan does not give rise to extreme partisan outcomes. Equally important, we illuminate anomalous structures in the plans of interest by developing graphical representations which help identify and understand instances of cracking and packing associated with gerrymandering. These methods were successfully used in recent court cases. Supplementary materials for this article are available online.

We develop methods to evaluate whether a political districting accurately represents the will of the people. To explore and showcase our ideas, we concentrate on the congressional districts for the U.S. House of Representatives and use the state of North Carolina and its redistrictings since the 2010 census. Using a Monte Carlo algorithm, we randomly generate over 24,000 redistrictings that are non-partisan and adhere to criteria from proposed legislation. Applying historical voting data to these random redistrictings, we find that the number of democratic and republican representatives elected varies drastically depending on how districts are drawn. Some results are more common, and we gain a clear range of expected election outcomes. Using the statistics of our generated redistrictings, we critique the particular congressional districtings used in the 2012 and 2016 NC elections as well as a districting proposed by a bipartisan redistricting commission. We find that the 2012 and 2016 districtings are highly atypical and not representative of the will of the people. On the other hand, our results indicate that a plan produced by a bipartisan panel of retired judges is highly typical and representative. Since our analyses are based on an ensemble of reasonable redistrictings of North Carolina, they provide a baseline for a given election which incorporates the geometry of the state's population distribution.

We derive an exact solution for Stokes flow in a channel with permeable walls. At the channel walls, the normal component of the fluid velocity is described by Darcy's law and the tangential component of the fluid velocity is described by the no slip condition. The pressure exterior to the channel is assumed to be constant. Although this problem has been well studied, typical studies assume that the permeability of the wall is small relative to other non-dimensional parameters; this work relaxes this assumption and explores a regime in parameter space that has not yet been well studied. A consequence of this relaxation is that transverse velocity is no longer necessarily small when compared with the axial velocity. We use our result to explore how existing asymptotic theories break down in the limit of large permeability for channels of small length.