This paper presents a comparison study between 10 automatic and six interactive methods for liver segmentation from contrast-enhanced CT images. It is based on results from the "MICCAI 2007 Grand Challenge" workshop, where 16 teams evaluated their algorithms on a common database. A collection of 20 clinical images with reference segmentations was provided to train and tune algorithms in advance. Participants were also allowed to use additional proprietary training data for that purpose. All teams then had to apply their methods to 10 test datasets and submit the obtained results. Employed algorithms include statistical shape models, atlas registration, level-sets, graph-cuts and rule-based systems. All results were compared to reference segmentations five error measures that highlight different aspects of segmentation accuracy. All measures were combined according to a specific scoring system relating the obtained values to human expert variability. In general, interactive methods reached higher average scores than automatic approaches and featured a better consistency of segmentation quality. However, the best automatic methods (mainly based on statistical shape models with some additional free deformation) could compete well on the majority of test images. The study provides an insight in performance of different segmentation approaches under real-world conditions and highlights achievements and limitations of current image analysis techniques.

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• In major blunt trauma, rib fractures are diagnosed with Computed Tomography. • Image processing can unfold all ribs into a single plane. • Unfolded ribs can be read twice as fast as axial images. • Unfolding the ribs allows a more accurate diagnosis of rib fractures.

Abstract. Probabilistic models are extensively used in medical image segmentation. Most of them employ parametric representations of densities and make idealizing assumptions, e.g. normal distribution of data. Often, such assumptions are inadequate and limit a broader application. We propose here a novel probabilistic active shape model for organ segmentation, which is entirely built upon non-parametric density estimates. In particular, a nearest neighbor boundary appearance model is complemented by a cascade of boosted classifiers for region information and combined with a shape model based on Parzen density estimation. Image and shape terms are integrated into a single level set equation. Our approach has been evaluated for 3-D liver segmentation using a public data base originating from a competition (http://sliver07.org). With an average surface distance of 1.0 mm and an average volume overlap error of 6.5 %, it outperforms other automatic methods and provides accuracy close to interactive ones. Since no adaptions specific to liver segmentation have been made, our probabilistic active shape model can be applied to other segmentation tasks easily.

High performance deformation of volumetric objects is a common problem in computer graphics that has not yet been handled sufficiently. As a supplement to 3D texture based volume rendering, a novel approach is presented, which adaptively subdivides the volume into piecewise linear patches. An appropriate mathematical model based on trilinear interpolation and its approximations is proposed. New optimizations are introduced in this paper which are especially tailored to an efficient implementation using general purpose rasterization hardware, including new technologies, such as vertex programs and pixel shaders. Additionally, a high performance model for local illumination calculation is introduced, which meets the aesthetic requirements of visual arts and entertainment. The results demonstrate the significant performance benefit and allow for time-critical applications, such as computer assisted surgery.