Subcutaneous fat necrosis of the newborn is a rare benign panniculitis found in term and post-term neonates. Diagnosis is based on clinical characteristics and specific alterations in the adipocytes, detected by anatomical pathology. Subcutaneous fat necrosis of the newborn can occur in uncomplicated pregnancy and childbirth. However, perinatal complications such as asphyxia, hypothermia, seizures, preeclampsia, meconium aspiration, and even whole-body cooling used in newborns with perinatal hypoxia/anoxia may be associated with this entity.

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Atopic Dermatitis is a very heterogeneous and complex disease. Recently, the ethnic background has been reported as a determining factor for a better understanding of genetic differences, clinical phenotypes, and immune activation patterns in patients with AD. In the future, therapeutic interventions should consider these immunophenotypes for individualizing treatment of atopic dermatitis.