No abstract

In this study we screened Viburnum grandiflorum for bioactive secondary metabolites and biological activity. Secondary metabolites were detected by phytochemical tests, and biological activity was confirmed through antimicrobial and anti-oxidant assays. Phytochemical screening (alkaloidal, tannins, terpenoids, flavonoids, anthraquinones, and glycosides) was performed with methanol, and aqueous and ethyl acetate extracts. Antibacterial activity against four bacterial strains -staphylococcus auries, Escherichia Coli, Bacillus subtillus, and salmonella typhi -were measured. Methanolic extract showed maximum inhibitory activity with diameter of zone of inhibition (11.66 mm), followed by n-hexane extract (9.33 mm) and then ethyl acetate extract. Four different fungi (Penicillium chrysogenum, Aspergillus flavus, Rhodotorula mucilaginosa, and Stachybotrys chartarum) were also tested against plant stem extract using different solvents. Dimethyl sulfoxide extract showed a maximum zone of inhibition at 20 mg/ml. Anti-oxidant activity of stem extract of Viburnum grandiflorum was evaluated by 1, 1-diphenyl-2-picryl-hydrazyl (DPPH). Then we measured absorbance, and percentage activity at each concentration was found for three solvent extracts to get Ic50 values. These data support Viburnum grandiflorum as having enough potential to be used safely as an antimicrobial drug.

This study focuses on evaluating total phenolic contents (TPC) in Taraxacum officinale (L.), a member of the family Asteraceae (compositae). The TPC were estimated by Folin-Ciocalteu's reagent and gallic acid was taken as standard. The amount of phenolics was communicated as gallic acid equivalent (GAE). The TPC varied from 41.47 mg/g to 691.6 mg/g in the Taraxacum officinale (L.) extracts. The maximum phenolic contents were found in hydro-alcoholic extract (691.6 mg/g GAE) in comparison with aqueous extract. These extracts have a significant role as antibacterial and antimicrobial agents.

No abstract

In this study, antibacterial activity of the prepared nanocomposites [poly (o-methoxy-aniline); POMA] at different concentrations was tested on bacterial strains. Nanocomposites were prepared by in situ chemical polymerization of ortho anisidine monomer in acidic medium with ammonium peroxydisulphate (APS) as an oxidant. The composition, structure and morphology of the polymer and nanocomposites were characterized by Fourier transform infrared spectroscopy (FTIR), x-ray diffraction (XRD) and ultraviolet-visible (UV-vis) spectroscopy. Different concentrations of nickel nanoparticles (1%, 2%, 3%, 4%, 5%) were used to confirm the characteristics of the synthesized nanocomposites. Antibacterial activity was tested against two strains: E. coli and S. typhi. A significant increase in the antibacterial activity of nanocomposites has been observed with an increase in concentration of nickel nanoparticles (Ni NPs). Excellent antibacterial activity was observed with nanocomposite having 5% Ni NPs.