BACKGROUND: This article focuses on the health risk assessment associated with air pollution for the population of the Temir district in the Aktobe region. The risk assessment of the effects of air pollution on public health revealed a tendency to deterioration in the health indicators of the children’s population. AIM: The research object was the population of the Temir district living near the oil and gas field Zhanazhol. METHODS: The work was carried out according to the risk assessment methodology described in the manual R 2.1.10-1920-04. The maximum non-carcinogenic risk due to exposure to chemicals in the air basin of residential areas was established for children from 0 to 6 years of age in the Temir district. RESULTS: A high risk of respiratory, blood, and cardiovascular diseases was observed. Sulfur dioxide, hydrogen sulfide, nitrogen, and carbon oxides contained in atmospheric air contribute to the risk of developing these diseases. The levels of carcinogenic risk to public health in the Temir district show that the maximum individual risk of oncological diseases is observed in the group of children. The risk of malignant neoplasms in adolescents is 1.2 times lower, in the male population – 1.4 times lower, on average, and in the female population – 1.3 times lower than in children. Public health risk analysis aims to select the best ways in a particular situation to eliminate or reduce risk associated with air pollution for the population. CONCLUSION: The methodology of a comprehensive health risk analysis is a promising and developing approach in the system of monitoring the quality of the human environment and assessing environmental hazards.

The article analyzes statistical data for the adult population of the oil and gas producing region at the Aktobe district over 2011-2015. Data on the incidence of malignant (reporting statistical forms No. 35 and No. 7) of the adult population of Mugalzhar, Temirsky district in the Aktobe region were studied in the process of the implementation of the research. In the work, there were used statistical and epidemiological methods. There was a decline in the primary incidence of malignant tumors (MT) in the adult population in Mugalzhar region (there is a gradual decrease from 2011 till 2014, in 2015 -the sharp decrease of the indices of the primary incidence) and Kobdinsky region (there is a decrease of the MT from 2013 and an increase in the rate of growth in Temirsky region (the incidence of MT decreases from 2011 till 2013, the trend of increasing primary indices is traced from 2013) during the period under review. Ranking of the MT with the first time established diagnosis among the adult population living in the Mugalzhar district showed the women’s breast cancer to held the first place, the second - the esophagus, the third place is the uterus. The elderly population of the Temir district is ranked first with MT of the esophagus, on the second - MT of tracheaetracheae, bronchus, lung, in third place - MT of the women’s breast. Among the adult population of the Kobda district, which is the control, the MT of the stomach is leading, after it the MT of tracheae, bronchus, lung, the MT esophagus is on the third place. The statistically significant direct, strong correlations between the annual average daily concentration of carbon monoxide, nitric oxide, hydrocarbon in the atmospheric air and the index of the MT incidence (body of uterus, uterine cervix, breast, mammary gland) at the adult population was revealed. In the Mugalzharsky and Kobdinsky districts the proportion of people living by 2015 more than 5 years from the date of diagnosis is higher than in the Temir district. In the Temir district, the detection rate among newly registered MT patients, in comparison with the Mugalzhar and Kobdinsky regions is high at the I-II stages, and at the IV stage.

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The formation of the health of adolescent children is carried out under the influence of many risk factors, including non-medical determinants: lifestyle, socio-economic, household factors and living conditions. Conducting epidemiological studies to identify the leading risk factors for the lifestyle and quality of life of adolescents is currently consistent with the basic directions of development of preventive medicine. Aim. Analysis of literature data, leading factors, the impact of social determinants on the health and well-being of children and adolescents. Material and methods. The choice of publications was made according to keywords that reflected between the indicators of the health of children and adolescents and the factors that influence them. Assessment of the influence of social determinants on the health of children and adolescents made it possible to prepare comprehensive measures to improve the health and health of children and adolescents. Conclusions. In the literature review, the social conditions studied have a decisive influence on the formation of the lifestyle, health and well-being of children and adolescents. Keywords: сhildren, adolescents, social determinant.