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Two cases of magnetic resonance (MR) imaging of intracranial abnormalities resulting from carbon monoxide toxicity are presented. Both cases demonstrate lesions in the globus pallidi of high MR signal intensity that correspond to previously reported abnormalities; the second case illustrates bilateral cortical high signal intensity lesions. The superiority of MR imaging in comparison with computed tomography is demonstrated in one case. The known effects of carbon monoxide toxicity in the brain are correlated with the findings of MR imaging.

Sixteen patients with various types of cancer who developed pain along the axial spine were prospectively studied by magnetic resonance imaging (MRI). The studies were performed with a Fonar Beta-3000 (Fonar Co., Melville, NY) permanent magnet operating at 0.3 Tesla (T). Detailed neurologic examinations were followed by bone x-rays, bone scans, and MRI. In 12 patients there were focal neurologic findings. Bone x-rays and bone scans were diagnostic for metastatic disease in 10 cases; MRIs were consistent with metastatic spinal-epidural disease in all 16 patients. Magnetic resonance imaging revealed bone involvement in three patients whose x-rays and bone scans were both negative indicating a higher degree of sensitivity. In six patients thecal compression was obvious on MRI; in three of these previous myelograms had been interpreted as negative. These early results suggest that MRI can serve as a useful tool for diagnosing early spinal-epidural metastases.

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