RESUMOSoutheast area was what more presented cases of intoxications, about 56%. In the whole country the age group more assault was 1-4 year-old children representing 27,7% of the registered cases. Therefore, the promotion of the use and rational access of the medicines is made necessary, tends in view the amount of cases of intoxications in humans happened in the studied period. It is worth to emphasize, that the presented numbers can still be larger since the notifications to SINITOX have voluntary character, fact that hinders the estimate faithful of the intoxication index for medicines in Brazil.

RESUMOSaneantes são preparações com finalidade de higienizar, desinfetar domicílios, ambientes, podendo ser usados também em alimentos. Nesse contexto o presente artigo objetivou revisar por meio da literatura, como os saneantes do País são aplicados a fim de limpar, reduzir e/ou matar microrganismos, não apenas apresentando os resultados encontrados, mas também discutindo a sua composição, mecanismo de ação e importância. Trata-se de um estudo de revisão sistemática, no qual foram utilizadas as seguintes palavras-chave: Saneante e Sanitizing, nas bases de dados LILACS, PubMed e SciELO, onde foram gerados 595 artigos, dos quais 23 obedeceram aos critérios de inclusão, e desses, 11 estavam dentro da temática. Os estudos encontrados mostraram uma grande diversidade de saneantes, naturais como os óleos essenciais e químicos como ozônio e amônia que foram abordados em mais de um estudo. Em relação à aplicação, foram encontrados saneantes, com propósito de ação em vários microrganismos, sendo os principais, as bactérias, como Staphylococcus aureus, Escherichia coli e Salmonella spp. a maioria com resultados positivos. A literatura mostrou a diversidade de aplicações dos saneantes que uma vez usados de forma correta impedem o crescimento de microrganismos potencialmente patogênicos, prevenindo diversas doenças contagiosas.Palavras chaves: Microrganismo. Eficácia. Saneantes. ABSTRACTSanitizing products are preparations with the purpose of sanitize, disinfect homes, environments, and may also be used in food. In this context, the present article aimed to review, through literature, such as the sanitizing of the Country are applied in order to clean, reduce and/or kill micro-organisms, not only presenting the found results, but also discussing its composition, mechanism of action and importance. This is a study of systematic review, in which we used the following keywords: Saneante and Sanitizing, in the databases LILACS, PubMed and SciELO, where they were generated 595 articles, of which 23 have obeyed the inclusion criteria, and of these, 11 were within the theme. The studies found showed a large variety of sanitizing products, natural essential oils and chemicals, such as ozone and ammonia, which have been addressed in more than one study. In relation to the application, have been found sanitizing products, for the purpose of action in various micro-organisms, being the main, the bacteria, such as Staphylococcus aureus, Escherichia coli and Salmonella spp., the majority with positive results. The literature showed the diversity of applications of the sanitizing products that once used correctly prevent the growth of micro-organisms potentially pathogenic, preventing several infectious diseases.

RESUMO O ácido ascórbico (Vitamina C) possui funções biológicas e metabólicas importantes na resposta imunitária do organismo, na redução do envelhecimento cutâneo e na absorção do ferro. O objetivo do presente trabalho foi avaliar a qualidade físico-química de três marcas de comprimidos efervescentes de ácido ascórbico 1g, incluindo referência e similares, comercializadas em Farmácias de Juazeiro do Norte -CE. Tratou-se de um estudo experimental e comparativo de análise quantitativa, realizado no mês de setembro de 2016. Todos os testes seguiram a Farmacopeia Brasileira 5º edição e foram efetuados no Laboratório da Faculdade de Juazeiro do Norte (FJN). No teste do peso médio a amostra A e C ficaram dentro do intervalo de ±5%, já a amostra B dois comprimidos ficaram fora sendo permitido até dois fora da margem. Já na resistência mecânica tais como dureza e friabilidade os resultados respectivamente foram amostra A (75,9 N / 6,208%), amostra B (39,9N / 3,031%) e amostra C (55,2N / 1,664%). No pH foram vistos que todos estavam dentro da variação aceitável de até 5,4. No teste de doseamento somente as amostras A e B ficaram dentro do intervalo de 90% e 110%. Conforme observado, as três amostras não atenderam às especificações, não garantindo a segurança, eficácia e qualidade desejadas.Palavras-chave: Ácido ascórbico. Comparativo. Controle de qualidade. ABSTRACTThe ascorbic acid (Vitamin C) has important metabolic and biological functions in the body's immune response, reduction of cutaneous aging and in the absorption of iron. The objective of this work was to evaluate the physical-chemical quality of three brands of effervescent tablets of ascorbic acid 1g, including reference and similar, marketed in pharmacies in Juazeiro do Norte -CE. This was an experimental and comparative study of quantitative analysis, held in September 2016. All tests followed the Brazilian Pharmacopoeia 5th edition and were performed in the Laboratory of the College of Juazeiro do Norte (FJN). In the average weight test, samples A and C were within the range of ±5%; two pills of sample B were outside, being allowed up to two out of margin. In the mechanical resistance, such as hardness and friability, the results were sample A (75.9 N / 6.208%), Sample B (39.9N / 3.031%) and sample C (55.2N / 1.664%). In pH, they were all within the acceptable range of up to 5.4. In the dosage test, samples A and B were within the range of 90% and 110%. As observed, the three samples did not meet the specifications, not ensuring the safety, efficacy and quality desired.

No abstract

According to Brazilian Constitution, Health is a right of all population and should be provided by the State. Some public policies used to and continued to be adopted with the intention of elevating the quality of the health services and enlarging the access of the population to the essential medications; to an example of those policies, the federal government instituted in 2004 the Popular Pharmacy Program of Brazil (PPPB). The present article has as objective describing the socioeconomic and pharmacotherapeutic profile of the users of the Popular Pharmacy Program attended in the Juazeiro do Norte's unity in the region of Ceará. It is an exploratory, descriptive study, with the quantitative approach with 100 interviewees of both sexes sample, between 20 and 70 years old, being the collection of data accomplished through a semi-structured questionnaire. Among the 100 participants of the research, 77% were female. 22% of the interviewees aged 61-70 years; 79% affirmed to be no literateness; 78% claimed to have 1-2 minimum wages income; 22% of the respondents were hypertensive; 61% said the medicines they used were for hypertension control; 96% affirmed that PFPB met their expectations, and 69% declared having no conditions to finance the medication treatment. Besides the perspective of public health, the PFPB plays an important social role of the public compromises with to the disadvantaged Brazilian citizens. Amid the current discussions about the PFPB effectiveness and viability, it was possible to suggest strategies allowing to improve the program, such as the revision of the medicines list and the inclusion of more drugs, as well to enlarge the PFPB popularization.