Ground Water quality has a special significance for drinking, hygiene sanitation and domestic water supply. The study aims to understand the distribution of ground water quality in solid waste landfill of Bengkulu City. The following objectives of the study are to determine ground water quality parameters such as pH, total dissolved solid, electrical conductivity, hardness, iron, manganese, nitrate and nitrite. Sampling was carried out at a radius of 0 - 250 meters from the location of the landfill. The results of the pH at 10 sampling points show the values that are quite varied between 6,45 – 7,59; conductivity between 56 µS – 492 µS; TDS between 28 mg/L – 246 mg/L; salinity 32 mg/L – 284 mg/L; Iron (Fe) 0,040 mg/L – 0,323 mg/L; Manganese (Mn) 0,089 mg/L – 0,295 mg/L; Nitrate (NO3-) 0,2 mg/L – 0,8 mg/L and Nitrite (NO2-) 0,006 mg/L – 0,033 mg/L. Based on an assessment with the STORET system, water quality in the study area is classified as good (score =-4) by parameters such as temperature, pH, total dissolved solid, electrical conductivity, hardness, iron, manganese, nitrate and nitrite. By the total sampling sites, all sample site had good-quality water for hygiene sanitation based on STORET method.

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One of Bengkulu's local culture is the utilization of medicinal plants by the people of Bengkulu, especiallySouth Bengkulu, namely "Simbagh Utak" (Hydnophytum formicarum) for treating various diseases including Gout. However, they still use naturally, there is no scientific studied. This study was aimed to analyze the effect of "Simbagh Utak" (H. formicarum) on the reduction of serum uric acid levels in hyperuricemia male mice. This study used 25 male mice, that devided into 5 groups. The control group was given pellet feed (G1). We injected the high purine feed treatment per-oral to induce hyperuricemia (Negative control, G2) and then given H. formicarum extract 5.3mg/30gW (G3), 10.2mg/30gW (G4) and 21,2mg/30gW (G5). Uric acid measurements were performed using a digital method with easy touch /GCU. The tubers were extracted with maceration, eluent selection and isolation of the isolated components was carried out using thin layer chromatography and column chromatography. The extraction results were analyzed of functional groups using FTIR. The result showed that "simbagh utak" extract 5.3mg/30gW, 10.2mg/30gW and 21,2mg/30gW could reduce uric acid levels of hyperuricemia male mice 34.1%, 48.0% dan 53.4% respectively. On this basis, we conclude that "Simbagh Utak" extract could reduce levels of uric acid M. musculus males who have experienced a state of hyperuricemia (excess uric acid) very significantly at a dose of 21.2mg /30gW.

This study aims to determine the immunomodulatory activity of lemongrass essential oil on the proliferation of mouse lymphocyte cells in vitro. The method used is steam distillation to obtain citronella essential oil. Isolation of lymphocyte cells was obtained from the spleen organ of Swiss-Webster strain mice which was carried out aseptically. The lymphocyte cell proliferation test was carried out using the MTT Assay method and the absorbance was measured using an ELISA reader at 550 nm. The results showed that the lemongrass essential oil contained positive alkaloids, flavonoids, saponins, and steroids/triterpenoids with an essential oil yield of 0.043%. The higher the volatile oil concentration, the higher the Optical Density (OD) value obtained, but the OD increase at a 50 to 100 g/mL concentration was not significantly different. In conclusion, lemongrass essential oil has immunomodulatory activity against lymphocyte cell proliferation in mice tested in vitro. Keywords: Immunomodulator, Essential Oil, Lemongrass (Cymbopogon citratus), Immune System

Massive land conversion into palm oil tree plantation causes massive plantation waste (palm fronds) and the decrease of animal food in Jenggalu Village, Sukaraja, Seluma, Bengkulu. The solution for the problem is by utilizing palm fronds as silage (fermented animal food). The purpose of this community service is to improve the ability of female farmer group (Kelompok Wanita Tani/ KWT) Tanjung Aur in utilizing palm fronds as silage. The method applied is theory and practice on how to create silage, preparing the procedure to create silage along with the main ingredients, and then holding the workshop on processing food fermentation from palm fronds using EM-4 activator. To maintain the continuity of the program, besides choosing the person in charge of the equipment, a supervision was also done in the form of monitoring and evaluation. After the fermentation process is completely applied for the livestock, the obtained results indicate that cows really like the food, this can be seen from the consumption increase. From the observation, the animal food and its technology are categorized as ‘useful’ and ‘very useful’ based on KWT members’ understanding. From the activity, it can be concluded that the KWT members’ ability towards the technology of utilizing palm fronds as silage is improved and it will be continuously applied.