l-Methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]-4(líf)-pyridinone, a New Herbicide l-Methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]-4(lff)-pyridinone (EL-171), a new chemical compound, is herbicidally active at low dosages and is safe for use on cotton. EL-171 controls a wide variety of annual grass and broadleaf weeds and is more active preemergence than postemergence. Susceptible plants treated preemergence with EL-171 emerge with chlorotic leaves, become necrotic, and subsequently die. EL-171 is a slow-acting, translocated herbicide, and treated plants appear unable to direct the synthesis of chlorophyll.

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This essay is based on Jour main sources of evidence: first, the fabric of the church itself; secondly, the very important but all too Jew contemporary records relating to its early history; thirdly, the very few drawings and literary descriptions of its state in recent centuries; and finally, the completely new evidence provided since 1974 by archaeological excavations under the direction of Professor Martin Biddle and his wife Birthe Kj11lbye-Biddle.The reconstruction arising from these studies differs in several ways from those that have been made in the past, even from those of my own most recent works. In particular the greater part of this essay is devoted to the much clearer picture that can now be given of the successive changes through which the church developed before the Viking occupation of Repton in 873-74. Many later changes were made in the Anglo-Saxon fabric, and these are described in sufficient detail to give a clear picture of the present state of the early fabric.

Antimutagenic fractions from collards yielded indole-3-carboxaldehyde [4] and traces of indole-3-acetonitrile [2]. The compounds had no antimutagenic activity. An analytical procedure for various indoles in plants was developed based on reversed-phase hplc. The indoles studied included the 3-carbinol 1, the acetonitrile 2, the carboxaldehyde 4, the 3-carboxylic acid 5, and the 3-acetic acid 6. Many Cruciferae and non-Cruciferae were analyzed. The latter did not contain measurable quantities of these compounds. In the case of the Cruciferae--with the exception of collards, which consistently indicated the presence of the aldehyde 4--major indole found was the nitrile 2. Although a particularly careful search for the carbinol 1 was conducted, only trace levels were noted. A review of the literature indicates that the content and occurrence of this indole in plants have been heavily overestimated. Because of the low levels found in the Cruciferae, our studies indicate that the role of the compound as a dietary factor may be questionable.

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