The current study was undertaken to evaluate in vitro the antileishmanial activity of three plants growing wild in Algeria : Juglans regia, Lawsonia inermis and Salvia officinalis. The hydroalcoholic extracts of these plants were tested on the growth of the promastigotes of Leishmania major. The plant extract effects were compared with three controls : CRL1 composed of 1 ml RPMI inoculated with 10 6 of promastigotes, CRL2 composed of 1 ml RPMI inoculated with 10 6 of promastigotes and 100 μl of hydroalcoholic solvent, CRL3 composed of 1 ml RPMI inoculated with 10 6 of promastigotes and 100 μl of Glucantim as a reference drug in the management of leishmaniasis. The results showed that both J. regia and L. inermis extracts reduced the promastigotes number significantly (P<0.01). however, S. officinalis showed a total inhibition of the Leishmania major growth.

The purpose of this study is to evaluate the effect of housing systems (free vs. tie-stall) and season (winter vs. spring) on the welfare of dairy cows through indices of cleanliness, leg health (straightness, hocks and knees), lameness score, body condition and milk production. This is to test the hypothesis that dairy cows in spring and free-stalls have a better quality of well-being than those kept in tie stalls in winter. For that, 299 dairy cows of the Holstein and Montbeliard breeds were selected from dairy farms in 6 communes of the Constantine governorate in eastern Algeria. The results showed that tie-stalled farms in winter were characterized by a lack of hygiene (P <0.001), with a stall cleanliness score of 7.62 and a frequency of 32.60% of dirty to very dirty cows. In the spring, the incidence of severe lameness does not exceed 9% in farms with tie stalls and more than 41% in mild lameness in housing with free stalls (P <0.001). Cows in tie stalls show a deviation of legs of 17° to 24° (57.97%). On the other hand, more than half of cows in free stalls show integumentary lesions (alopecia and swelling) of the carpal (60.25%) and tarsal joints (54.22%) (P <0.001). The percentage of fairly lean cows (score 2-2.5), housed in tie stalls, was significantly higher (18 to 44%) with a significantly low milk production (P <0.001). These results reflect a lack of comfort in tie-stall farms during winter which has an impact on dairy performance.