To evaluate the prevalence of ocular surface disorder (OSD) in patients using anti-glaucoma medications METHODS; 150 eyes of 75 glaucoma patients on topical anti-glaucoma medication with preservatives were studied. Patients with history of use of topical corticosteroids, cyclosporine, anti-inflammatory drugs or other topical medications within last 3 months were excluded. Patients completed Ocular Surface Disease Index questionnaire, underwent evaluation by Schirmer test, tear breakup time, corneal and conjunctival lissamine green staining. RESULTS; Mean age of patients was 56.5 (range 23-80) years. 50 (67%) patients were males and 25 (33%) patients were females.56% patients had primary open angle glaucoma. 41% patients had primary angle glaucoma. 3% patients had ocular hypertension. 44 (59%) patients were on single medication. 25 (33%) patients were on two medications. 6 (8%) patients were on three medications. Mean duration of using medication was 3.8 yrs (range; 5 months-16 yrs). Duration less than 1yrs-10(13%) patients. 1 to 5 yrs-36(48%) patients. 5 to 1yrs-19(26%) patients. More than 10yrs-10(13%) patients. 32% patients reported symptoms in at least one eye. Severe symptoms were reported by none. Tear breakup time was abnormal in 54.5% patients, severe abnormality in 20.5% patients. Schirmer testing showed 50.5% patients with decreased tear production in at least one eye, severe tear deficiency in 21.5% patients. Lissamine green staining of conjunctival and cornea showed positive results in 47% patients. None had severe staining. As
AIM:This study evaluates varied type of ocular manifestation associated with HIV/AIDS in co relation to CD4 count METHODS: All patients with HIV/AIDS attending KIMS ART center between August 2008 to August 2010 were enrolled.100 Cases which were proven HIV were enrolled in the study. Thorough ophthalmic examination was carried out in terms of slit lamp examination and fundus examination with 90D after dilatation of pupil. RESULTS: The posterior segment lesions (65%) were more commonly observed than anterior segment lesions (40%) in this study. The commonest manifestations encountered in this study were HIV retinopathy (30%), CMV retinitis (14%), Chorioretinitis (14%), Uveitis (8%), Complicated Cataract and Herpes zoster ophthalmicus (7%) each and Molluscum contagiosum and disc edema (4%) each, followed by dry eyes (3%). The other relatively rarer manifestations of this study were external hordeolum (2%), myopic fundus with cotton wool spots (2%) and Bell's palsy (2%), Kaposi sarcoma (1%), chronic dacryocystitis (1%), corneal opacity (1%) and Episcleritis (1%). CONCLUSION: In our study HIV retinopathy was most common ocular manifestation encountered with mild vision deterioration Page 4404 with relatively high CD4 count. CMV retinitis was next commonest lesion with varied degrees visual affection and CD4 count range. The posterior segment lesions being 65% and anterior segment lesions 35%.
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