RationaleTo prevent and control the COVID-19 pandemic, the biggest immunization campaign in history had been deployed worldwide. Therefore, it is important to inform the adverse events following immunization (AEFI) to populations.ObjectivesTo prevent vaccine hesitancy, this study focused on finding the common AEFI with the COVID-19 Comirnaty vaccine (Pfizer-BioNTech) among participants aged 18 and above and related factors in Hanoi, Vietnam.MethodsA cross-sectional study was carried out to collect participants’ data and AEFI after being vaccinated at Hanoi Medical University, Vietnam, in 2021. Logistic regression was utilized for analyzing the correlated factors of AEFI.ResultsWe recruited a random sample of 820 participants who received both basic doses of Pfizer vaccine in September and October 2021. The proportion of AEFI after the first dose, second dose, and both doses of Pfizer vaccine was 24.4%, 64.2%, and 18.5%, respectively. AEFI mostly appeared within 1 day and lasted for 1 to 2 days. The AEFI were more common in females (OR=1.7; 95%CI=1.25–2.29) and younger age groups (OR=1.9; 95%CI=1.37–2.58). History of allergy, allergic diseases, chronic diseases, and occupations were not statistically significant with AEFI.ConclusionOur findings indicated that the COVID-19 Comirnaty vaccine is safe to be injected. Gender and age group are important factors influencing AEFI.

An Fe3O4/polyguanidine nanocomposite with strong antibacterial activity was prepared from Fe3O4 nanoparticles, using spent pickling liquors as the iron source, which were then encapsulated with polyguanidine.

Spent pickling liquor is a considered hazardous waste because of its very high level of acidity and high metal concentration, and the conventional neutralization method regenerates an excessive quantity of sludge that poses a serious problem concerning to the landfill disposal and risk of ground water contamination. Therefore, recovery of spent pickling liquor is necessary. Several approaches have been investigated for spent pickling liquor recovery, but they are generally costly and lead to produce various iron salts or oxides which have a limited value. In the present study, we explore the potential of using spent pickling liquor as iron precursor for the synthesis of magnetic nanoparticles. Here, Fe3O4 nanoparticles were prepared easily by oxidation-precipitation from spent hydrochloride acid pickling liquors in aqueous saturated solution of calcium hydroxide at room temperature, in the air, and under suitable speed of rotation. The FT-IR, XRD and TEM results shown that monodisperse Fe3O4 nanoparticles in the size range of 10-25 nm were obtained, with a high level of crystallinity. The BET surface area was about 46 m2 g-1. The synthesized Fe3O4 nanoparticles exhibited the superparamagnetic behavior with relatively high saturation magnetization, Ms = 73 emu/g. The synthesis procedure of magnetic nanoparticles revealed here will provide a new possibility for spent pickling liquors recovery more effectively. For citation: Vu Minh X., Le Ha T. T., Pham Lan T., Pham Nam H., Le Huong T. M., Le Lu T. Nguyen Dung T. Synthesis of magnetic nanoparticles from spent picking liquors in aqueous saturated solution of calcium hydroxide. Izv. Vyssh. Uchebn. Zaved. Khim. Khim. Tekhnol. 2018. V. 61. N 9-10. P. 59-63

– HCTN7. Plasma cholesterol level plays an important role in atherosclerosis and cardiovascular diseases. Piperine, an alkaloid form of black pepper is known to reduce cholesterol uptake. In this paper, piperine-loaded chitosan nanoparticles (CTS-PIP NPs) were prepared by ionic gelation method. Molecular interactions among the components were confirmed by FT-IR spectroscopy. Transmission electron microscopy (TEM) images revealed spherical-shaped nanoparticles with diameter of <100 nm. CTS-PIP NPs displayed positive ζ-potential(ZP) of about 31.6 mV. Dynamic light scattering (DLS) particle size (PS) distribution analysis indicated the mean particle size of CTS-PIP NPs was 245.9 nm, polydispersity index of 31%