The current study was designed to investigate the effect of cholesterol supplementation at a dose of (260 mg/kg ration) and boiled extract of red pepper at a dose of (100 mg/kg body weight) on the Testosterone hormone, Thyroid stimulating hormone or Thyrotropin, thyroxine, thyronine, and it is effects on the body weights of male rabbits after 4, 8 weeks of the start of treatment. Forty local male rabbits aged (8-10) months old were randomly divided into four groups (10 animals/ group) to be treated as follows: First group: Standard ration and distilled water represented as control groups. Second group: Standard ration plus cholesterol at the dose (260 mg/ kg ration) and distilled water. Third group: Standard ration with drinking red pepper fruit boiled extract at the dose (100 mg/ kg body weight). Fourth group: Standard ration plus cholesterol (260 mg / kg ration) in addition to drinking red pepper fruits boiled extract at a dose of (100 mg/kg body weight). All groups were treated daily for eight weeks. Results showed that cholesterol treatment caused significant decrease(P≤0.05) in the hormones level, with a significant increase (P≤0.05) on the body weights of treated rabbit after 4 and 8 weeks. Furthermore, treatment with red pepper boiled extract led to a significant increase (P≤0.05) on the levels of the studied hormones, and a significant decrease (P≤0.05) in the body weights of treated rabbits.
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