The spermatogenesis process is very complex and involves many processes that lead to giving normal sperm, these sperms are very important for Fertility in the male. The cytokines are very important in male fertility which gives a significant job in fertilization. The varicocele patient grade 1,2 and 3(n= 25 , 25 and 25 Respectively) compared with control patient (n=13). The results of this study showed that cytokine level (interleukin 17 & 6) is a significant increase in varicocele patient compare with the control group, also a positive correlation was found between interleukin 17 & interleukin 6 in varicocele patient, while the result showed a negative correlation between interleukin 17 and the sperms concentration, sperm Progressive motility percent and sperm normal morphology present in a patient with varicocele grade 1,2 and 3 respectively (r= -0. 574, r = -0. 647and r = -0. 487). Also a negative correlation between interleukin 6 level and the sperms concentration , sperm Progressive motility percent and sperm normal morphology present in varicocele patient grade 1,2 and 3 Respectively (r= -0.467 , r = -0.324 and r = -0.307 ). The present study concludes that important role of interleukin 17 and interleukin 6 appears to be a key cytokine regulating local tissue inflammation, the study showed varicocele has a Harmful effect with the time on cytokines levels and increases the diameter.

Background: Seminal fluid is important factor for successful fertility, Sperm dysfunction is the most common cause of male infertility. Aim of study: To compare the sex hormone in patient with azoospermia, Oligozoospermia and Normospermia fertile men as a control To find out the causes of semen viscosity. Patients and methods: Data analysis from azoospermia patient (n = 35) and Oligozoospermia (n = 35) and Normospermia fertile men as a control (n = 13). Results: The results of this study revealed significant reduction (p andGLT;0.05) semen was reduced in azoospermia infertile patient (mean ± Std. Error 0.76 ± 0.21 also reduced in Oligozoospermia 0.71 ± 0.23 while showed no significant FSH and LH level between azoospermia and Oligozoospermia compare with Normospermia fertile men. Conclusion: The viscosity in semen has a strong relationship with low sperm counts is an important factor with sex hormones therefore it is the cause affecting the motile spermatozoa.