Excessive alcohol consumption by a pregnant woman may delay foetal development and may cause malformations. In this study, the model of the chicken embryo to demonstrate the teratogenic effect of ethanol (33%) on the chicken osteogenesis on the 10 th day of embryonic development have been used. 49 fertilized eggs were used in present investigation. Hence, different doses of ethanol were injected into the chicken embryos at 33% (20, 40, 80 μl) in the air space at gastrulation and, on the other hand, an equivalent amount of the mentioned doses of distilled water were injected into the control-group eggs which was done once in every two days in order to maintain a high concentration in the blood. Experiments were repeatedly and independently carried out for three times. The eggs were incubated in a humid incubator at the temperature of 37.7 °C and at 60-65% of humidity. On the 10 th day of incubation, the embryos were taken out and fixed in formalin at 10%. After that, the eggs were sectioned at 5μm of thickness with a Leica micrtome and, then, stained with the Hematoxylin and eosin. Histological examination has revealed that the exposition of chicken embryos to ethanol (33%) delays the skeletal development in a dose-dependent manner by reducing the length of the cartilaginous proliferation zone and hypertrophic zone during the bone formation period. Furthermore, under the effect of ethanol, the cell proliferation activities were repressed. In conclusion, present results indicated that using ethanol to treat chicken embryos at early stages caused considerable malformations and a decreased in the embryo survival rate. The exposition to alcohol affects the chicken osteogenesis in a dose-dependent manner.