Objectives: This study investigated the psychosocial risk factors of myocardial infarction and time related adverse effects of administration of streptokinase on short-term morbidity and mortality in patients with ST-segment-elevation myocardial infarction (STEMI). Methods: One hundred patients with STEMI treated with streptokinase in the hospital setting were prospectively enrolled in the study. The primary outcome parameter was the incidence of major adverse cardiac events. During hospital stay the psychosocial and demographic risk factors were also investigated. Results: The overall mortality rate was similar in both groups and it was not significant. (5.7% vs 14.5%; P = 0.18). The number of recurrent chest pain was significantly higher in the group 2 compared to the group 1 (25% vs 62.5%; P = .01). The number of hypotesion was significantly higher in the group 1 as compared to the group 2 (30.7% vs 6.2%; P = .009). The demographic and psychosocial risk factors were recorded. Conclusions:The early intravenous administration of streptokinase in the hospital setting leads to a reduced rate of major cardiovascular events compared to delayed administration beyond 2 hours. However, mortality rates were not significantly affected. Secondary prevention should be targeted on modifiable demographic, dietary, and psychosocial risk factors of STEMI.

Peptic ulcer is considered as one of the most common disorder among gastrointestinal ailments all over the world which is mainly caused by Helicobacter pylori infection, abundant use of NSAIDs, excessive alcohol intake and stress etc. Treatment of peptic ulcer with synthetic drugs such as proton pump inhibitors, H2 receptor antagonists and other non-steroidal anti-inflammatory drugs reported to have adverse effects, relapses and drug interactions. Medicinal plants containing active phyto-constituents have been proven as useful source in the prevention and treatment of various diseases including gastrointestinal problems. Demands of herbal medicines are increasing in both developed and developing countries due to growing recognition of natural plants having lesser or no side effects, relatively less toxic, economical and easily available in surrounding place. Therefore, medicinal plants stand out as being exceptional for its ethnic, ethno botanical and ethno pharmaceutical uses. In this review an attempt has been made to compile some plants which may be used in treatment or prevention of peptic ulcers. This article summarizes the antacid, anti-ulcer and gastro protective properties of the most commonly available medicinal plants.

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