In this article, we proposed an intelligent clinical decision support system for the detection and classification of brain tumor from risk of malignancy index (RMI) images. To overcome the lack of labeled training data needed to train convolutional neural networks, we have used a deep transfer learning and stacking concepts. For this, we choosed seven convolutional neural networks (CNN) architectures already pre-trained on an ImageNet dataset that we precisely fit on magnetic resonance imaging (MRI) of brain tumors collected from the brain tumor segmentation (BraTS) 19 database. To improve the accuracy of our global model, we only predict as output the prediction that obtained the maximum score among the predictions of the seven pre-trained CNNs. We used a 10-way cross-validation approach to assess the performance of our main 2-class model: low-grade glioma (LGG) and high-grade glioma (HGG) brain tumors. A comparison of the results of our proposed model with those published in the literature, shows that our proposed model is more efficient than those published with an average test precision of 98.67%, an average f1 score of 98.62%, a test precision average of 98.06% and an average test sensitivity of 98.33%.

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heart disease is a major cause of death worldwide. Thus, diagnosis and prediction of heart disease remain mandatory. Clinical decision support systems based on machine learning techniques have become the primary tool to assist clinicians and contribute to automated diagnosis. This paper aims to predict heart disease using Random Forest algorithm enhanced with the boosting algorithm Adaboost. The model is trained and tested on University of California Irvine (UCI) Cleveland and Statlog heart disease datasets using the most relevant features 14 attributes. The result shows that Random Forest algorithm combined with AdaBoost algorithm achieved higher accuracy than applying only Radom Forest algorithm, 96.16%, 95.98%, respectively. We compare our suggested model to report machine learning classifiers. Indeed, the obtained result is supporting the efficiency and validity of our model. Besides, the proposed model achieved high accuracy compared to existing studies in the literature that confirmed that a clinical decision support system could be used to predict heart disease based on machine learning algorithms.

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Parkinson’s disease is a neurodegenerative disorder caused by loss of dopamine neurons in the substantia nigra pars compacta. Tremor, rigidity, and bradykinesia are the major symptoms of the disease. These motor impairments are often accompanied by affective and emotional dysfunctions which have been largely studied over the last decade. The aim of this study was to investigate emotional processing organization in the brain of patients with Parkinson’s disease and to explore whether there are differences between recognition of different types of emotions in Parkinson’s disease. We examined 18 patients with Parkinson’s disease (8 men, 10 women) with no history of neurological or psychiatric comorbidities. All these patients underwent identical brain blood oxygenation level-dependent functional magnetic resonance imaging for emotion evaluation. Blood oxygenation level-dependent functional magnetic resonance imaging results revealed that the occipito-temporal cortices, insula, orbitofrontal cortex, basal ganglia, and parietal cortex which are involved in emotion processing, were activated during the functional control. Additionally, positive emotions activate larger volumes of the same anatomical entities than neutral and negative emotions. Results also revealed that Parkinson’s disease associated with emotional disorders are increasingly recognized as disabling as classic motor symptoms. These findings help clinical physicians to recognize the emotional dysfunction of patients with Parkinson’s disease.