Objective To report the perioperative outcomes of 200 patients with gynecologic cancer who underwent surgery during the Novel Coronavirus Disease (COVID‐19) pandemic and the safety of surgical approach. Methods Data of patients operated between March 10 and May 20, 2020, were collected retrospectively. Data were statistically analyzed using IBM Statistical Package for the Social Sciences (SPSS) Statistics for Windows v. SP21.0. Results Data of 200 patients were included. Their mean age was 56 years. Of the patients, 54% (n=108), 27.5% (n=55), 12.5% (n=25), and 2% (n=4) were diagnosed as having endometrial, ovarian, cervical, and vulvar cancer, respectively. Of them, 98% underwent non‐emergent surgery. A minimally invasive surgical approach was used in 18%. Stage 1 cancer was found in 68% of patients. Surgeons reported COVID‐related changes in 10% of the cases. The rate of postoperative complications was 12%. Only two patients had cough and suspected pneumonic lesions on thoracic computed tomography postoperatively, but neither was positive for COVID‐19 on polymerase chain reaction testing. Conclusion Based on the present findings, it is thought that gynecologic cancer surgery should continue during the COVID‐19 pandemic while adhering to the measures. Postponement or non‐surgical management should only be considered in patients with documented infection. Gynecologic cancer surgery should continue during the COVID‐19 pandemic while adhering to measures. Only 1% of patients developed COVID‐19‐related symptoms during the postoperative follow‐up period.

In patients with EC, there is a significant difference between LR and HR groups for LNM and CSS rates. But this method of stratification is not adequate to separate them for deciding whether surgical staging is mandatory. Moreover, even most of the HR patients (163/184, 88.6%) are exposed to unnecessary LND. Perhaps they are not really HR and the HR definition needs to be revised.

The incidence of primary mucosal malignant melanoma (PMMM) is 1.3% among all malignant melanomas (MM). Cervical involvement is very rare; the number of cases of cervical PMMM reported so far is around 80. In our patient, a dark color, 2-cm diameter, nonulcerated tumor formation was observed upon examination of the cervix. Tumoral tissue consisted of atypical melanocytic cells containing numerous mitotic figures. In immunochemical studies, S-100, Melan-A, and HMB-45 positivity were observed. The tumor was 20 mm in invasion depth, Breslow IV, and FIGO stage IB1. Radical surgery was followed by adjuvant radiotherapy, and subsequently interferon treatment was applied. Examination and scans 20 months after surgery were free from tumor.

ÖZET Amaç: Endometrium kanseri (EK)'nde halen standart cerrahi her ne kadar tam evreleme şeklinde olsa da, erken evrede lenf nodu diseksiyonu (LND)'nun yeri tartışmalıdır. O nedenle yüksek riskli hastaların tespiti önem taşımaktadır. Bu çalışmada lenf nodu metastazı (LNM) için yüksek riskli hastaların operasyon sırasında frozen kesit (FK) ile kurumumuzda hangi doğrulukta tespit edilebileceğini görmek amaçlanmıştır. Yöntem: EK'li 37 hastada intraoperatif FK ile, histopatolojik tiplendirme, greyd, tümör çapı (TÇ), miyometrial invazyon derinliği (MİD) ve lenfovasküler emboli (LVE) parametrelerine bakıldı. Bu parametreler parafin takip (PT)'lerindeki nihai sonuçları ile karşılaştırıldı. Bulgular: FK incelemede histopatolojik tip I tanı alan bir hasta (%2,7), PT'te tip II olarak değerlendirildi. MİD değerlendirmesinde FK incelemede bir hasta derin invazyon açısından yanlış negatif (%2,7) tanı aldı. TÇ ölçümü FK ve PT tüm hastalarda uyumlu idi. LVE bakıldığında, FK incelemede 4 hastada (%10,8) LVE tespit edilemedi. Tümörler diferansiasyon açısından derecelendiğinde nükleer yüksek greyd 5 hastada (%13,5), yapısal yüksek greyd ise 3 hastada (%8,1) FK ile yanlış negatif tanı aldı. Histopatolojik tip tayini, MİD, LVE, nükleer ve yapısal greyd için testlerin doğruluğu sırası ile %94, %97, %89, %86 ve %91 olarak hesaplandı. Tüm parametreler birlikte değerlendirildiğinde EK hastalarda LNM için yüksek riskli olanı yakalama açısından FK incelemenin duyarlılık, özgüllük ve doğruluğu sırası ile %96, %100 ve %97 olarak hesaplandı. FK inceleme yüksek riskli EK'ni yakalama açısından (1/37) bir hastada (%2,7) başarılı olamadı. Sonuç: EK'li hastada FK incelemenin histopatolojik tip tayini, TÇ ve MİD değerlendirmesi açısından başarılı fakat LVE, nükleer ve yapısal greyd tayini için doğruluk oranın düşük olduğu izlendi. Anahtar kelimeler: endometrium kanseri, risk, frozen, doğruluk, lenf nodu diseksiyonu ABSTRACT Aim: Although the current standard surgical procedure is still staging comprehensively in endometrial cancer (EC), the therapeutic effect of lymph node dissection (LND) is debatable for early stages. Therefore, it is important to identify high risk patients. In this study, it is intended to see the accuracy rate of frozen section (FS) in our institution by determining high-risk patients for lymph node metastasis (LNM) in EC. Method: Intraoperative FS were studied in 37 EC patients, histopathological typing, grade, tumor size (TS), myometrial invasion depth (MID) and lymphovascular emboli (LVE) parameters were measured. These parameters were monitored and compared with the final paraffin results (PR). Results: In FS examination, the histopathological diagnosis of a patient with type I was a type II in PR (2.7%). In MID assessment one patient was (2.7%) misdiagnosed. In TS measurement, FS and PR were consistent in all patients. Referring to LVE, 4 patients (10.8%) were false negative by FS examination. FS received a false negative diagnosis in 5 patients (13.5%) for nuclear high grade and in 3 patients (8.1%) for structural high...