required for the spermatozoa (Peterson and Freund -1971). The role of lipids in supplying the needed energy through oxidative processes still remains obscure. The aim of the present work was to demonstrate this role by determining the level of non-esterified fatty acids, triglycerides, fructose and lipoprotein lipase enzyme activity, immediately and 2 hours after liquifaction in the semen of normozoospermic, oligozoospermic and azoospermic men. Material and MethodsThe present study was carried out on the semen of 37 males. 20 of them were attending the male sterility clinic of Cairo university Hospital complaining of primary sterility. The remaining were fertile, had no relevant complaint and were selected from the Dermatology clinic. These males were divided into three groups: Group I: Control group composed of 17 fertile and clinically free males. Group 11: This group included 10 patients complaining of primary sterility. Members of this group were oligoasthenozoospermic and all were clinically free. Group 111: This group was composed of 10 patients complaining of primary sterility, their semen analysis showed azoospermia. Clinically, all of them were free. From the three groups semen was obtained by masturbation, left to liquify and a sample was examined immediately for: fructose (Karvonen and Malm -1975); non esterified fatty acids (NEFA) (Duncombe -1964); triglycerides (Lloyd and Goldrich -1968) and lipase (Kits produced by *Biomerieux Company). Two hours later, the rest of the ejaculate which was kept at room temperature was subjected to the same estimations. Resultsmediately and two hours after liquefaction are shown in the table. It is clear from the table that:The level of non esterified fatty acids (NEFA), triglycerides and fructose in semen im-
Summary Semen samples from 41 infertile male patients (30 with varicocele and 11 controls) were examined, lactic and pyruvic acids were measured and the oxygen consumption was determined. Decreased sperm count, diminished motility, decreased lactic acid concentration and oxygen consumption were noticed among the varicocele patients as compared to controls. Pyruvic acid concentration was slightly increased in the varicocele group. It was concluded that a decrease in lactic dehydrogenase activity may be one of the abnormalities in the semen of varicocele patients. Einfluß der Varikocele auf die Atmung und den Stoffwechsel der Spermatozoen Zusammenfassung In einer experimentellen Arbeit wurden die Spermaproben von 41 unfruchtbaren Männern (30 × Varikocele, 11 Kontrollen) hinsichtlich des Sauerstoffverbrauches der Spermatozoen sowie des Gehaltes an Milchsäure und Pyruvat im Sperma untersucht. Bei den Vari‐kocele‐Patienten fanden sich herabgesetzte Spermatozoendichte, verminderte Motilität sowie herabgesetzte Milchsäurekonzentration und verminderter Sauerstoffverbrauch. Pyruvat war in der Varkocele‐Gruppe geringgradig erhöht. Es wird festgestellt, daß möglicherweise eine herabgesetzte Milchsäure‐dehydrogenase‐Aktivität eine der Abnormitäten im Sperma von Männern mit Varikocele ist.
Zusammenfassung Unfruchtbarkeit des Mannes: Ätiologische Faktoren bei 385 Männern Anhand von Untersuchungen bei 385 Männern mit Infertilität wird zum Problem der verschiedenen ätiologischen Faktoren Stellung genommen. Mit 27,5% liegt die Gruppe der Männer mit Prostato‐Vesikulitis an der Spitze des Kollektivs; hier ergab sich in 3/4 dieser Fälle eine herabgesetzte Spermatozoenmotilität. Eine Varikocele fand sich in 21,8%, eine idiopathische Infertilität lag in 10,9%, eine Verschlußazoospermie in 6,5% und Autoagglutination der Spermatozoen in 5,7% vor, während alle anderen Faktoren (Hodenatrophie, Kryptorchismus, endokrine Störungen, Veränderungen des Ejakulates, Nekrozoospermie) etwa je 1,0% ausmachen. Zu den verschiedenen Faktoren werden Erläuterungen im Zusammenhang mit den eigenen Befunden gegeben. In die Gruppe „idiopathisch” sind auch die Fälle einbezogen worden, bei denen eine chromosomale Störung vorlag bzw. eine Exposition gegenüber Streß‐Situationen und gegenüber antispermatogenetisch wirkenden Chemikalien gegeben war. Die Autoren hoffen, diese Gruppe in einer späteren Mitteilung aufklären zu können.
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