Firefighters are exposed to both known and suspected carcinogens. This study aims to systematically review the literature on the association of firefighting occupation and cancer incidence and mortality, overall and for specific cancer sites. A systematic review using PubMed, Embase, and Web of Science was performed up to January 1, 2018. We extracted risk estimates of cancers and calculated summary incidence risk estimates (SIRE), summary mortality risk estimates (SMRE), and their 95% confidence intervals (CI). Publication bias and risk of bias in individual studies were assessed using Begg's and Egger's tests and the Newcastle‐Ottawa scale (NOS), respectively. We included 50 papers in the review and 48 in the meta‐analysis. We found significantly elevated SIREs for cancer of the colon (1.14; CI 1.06 to 1.21), rectum (1.09; CI 1.00 to 1.20), prostate (1.15; CI 1.05 to 1.27), testis (1.34; CI 1.08 to 1.68), bladder (1.12; CI 1.04 to 1.21), thyroid (1.22; CI 1.01 to 1.48), pleura (1.60; CI 1.09 to 2.34), and for malignant melanoma (1.21; CI 1.02 to 1.45). We found significant SMREs of 1.36 (1.18 to 1.57) and 1.42 (1.05 to 1.90) for rectal cancer and Non‐Hodgkin's lymphoma, respectively. Considering the significantly elevated risk of some cancers in this occupational group, we suggest improving preventive measures and securing adequate and relevant medical attention for this group. Further studies with more accurate and in‐depth exposure assessments are indicated.
The results suggested that occupational exposure to ELF-MF might increase the risk of AD. However, this suggestion should be interpreted with caution given the moderate to high heterogeneity and indication for publication bias.
Background: Fatigue, as a destructive phenomenon, can have adverse effects on various aspects of workers' lives. Job burnout is one of the important consequences of fatigue among employees including nurses in different workplaces, especially healthcare centers. Objectives: The present study aimed to assess the relationship between fatigue and job burnout. Methods: This cross sectional study was conducted on 522 nurses, who were randomly selected from teaching hospitals of Shiraz University of Medical Sciences (SUMS), Shiraz, Iran. Fatigue dimensions and job burnout were measured by Multidimensional Fatigue Inventory (MFI-20) and Maslach Burnout Inventory (MBI), respectively. Results: The results revealed that among burnout dimensions, depersonalization and diminished personal accomplishment had the highest mean scores, while emotional exhaustion had the lowest mean score. Among different fatigue dimensions, the highest mean score was related to general fatigue. Moreover, the results of Pearson's correlation test showed a significant positive relationship between emotional exhaustion and fatigue dimensions. Also, a significant direct correlation was found between depersonalization and general, physical, and mental fatigue. On the other hand, a significant negative correlation was observed between diminished personal accomplishment and all fatigue dimensions, except mental fatigue. Conclusions: Considering the adverse effects of fatigue on various aspects of nurses' job burnout, more attention should be paid to fatigue in healthcare facilities, especially hospitals. In addition, a suitable managerial program should be developed to decrease nurses' job burnout and other fatigue consequences and to improve working conditions.
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