A Schiff bases is a nitrogeneous analogue of an aldehydes or may be ketones whose (CO) carbonyl groups has been replace by an imines group or azomethine group. It is sometimes referred to as an imines or an azomethines group. -C=N- group-containing compounds with the imine prefix. These substances are also referred to as imines, however Hugo Schiff, who initially created these substances, is remembered by calling them Schiff bases . pharmaceutical activity of A Schiff bases Showed Antibacterial activites ,Bacterial that displaied many antimirobial resistance are closely linked to the rise in the mortalities rate of infectiouss  illnesses Antifungal activitie fungall infectionss are not often restricted to the surface tissuess; in fact, a considerable rise in systemic fungal infections that can be fatal has been noted.Antiviralogy activity Vaccinationn might result in the eradicationn of viral diseases including rubella, polio, and smallpox.