Introduction: Vitamin C, solvent in water, is necessary to synthesis and to keep collagen, and also is an intercellular surrounding material of body tissues, blood vessels, cartilages, bones, teeth, skins, and tendons. It is able to improve the protective mechanism of immune system, and wounds. Also, it is necessary to rehabilitate wounds and resistance against infection. This study makes an attempt to define the effect of topical vitamin C on improving second-degree burns.

Objectives Acute myocardial infarction (MI) and hospitalization are one of the most stressful situations for many patients. Aromatherapy is a branch of the complementary medicine that is effective in anxiety. The present study aims to determine the effect of aromatherapy with rose essential oil (REO) on apparent anxiety in patients with acute MI. Methods This randomized clinical trial was carried out on patients with acute MI admitted to the cardiac ward of Heshmatieh Hospital in Sabzevar. Eighty patients were randomly assigned to two aromas and placebo groups, who received three drops of REO or placebo by inhalation three times a day for 3 days. Before and after the intervention, patients’ anxiety levels were measured by the Spielberger questionnaire. Data were analyzed by chi-square and the independent and paired and t-tests. Results Before the intervention, the mean of apparent anxiety was not significantly different in the intervention and control groups (48.44 ± 3.81 and 51.38 ± 7.21, respectively, p=0.16) while this parameter was significant after the intervention in both experimental groups (47.27 ± 7.11 and 44.16 ± 4.63, respectively, p=0.000), with a reduction in the mean of apparent anxiety in the intervention group. Moreover, the results of paired t-test revealed that the anxiety scores decreased significantly in the test group before and after the intervention (51.38 ± 7.21 and 44.16 ± 4.63, p=0.000). Conclusions Considering the positive effects of REO used in this study to reduce anxiety in patients with acute MI, the use of REO is recommended as a complementary treatment to reduce anxiety in these patients.

Cancer disease and its treatment methods affect the quality of life of those suffering from breast cancer. Nausea and vomiting are frequent side-effects of chemotherapy. Nowadays, complementary therapies are used along with routine treatments to control this disease. This study aimed to evaluate the effect of sucking ice bits with plain water on nausea and vomiting during chemotherapy in patients with breast cancer. Methods In this clinical trial, participants were 60 breast cancer patients undergoing chemotherapy. They were randomly divided into two groups of control and ice. The ice group received 30 bits of ice in 1 cc during chemotherapy, while control group received 30-cc tap water. Nausea was evaluated based on visual analog scale and vomiting was estimated based on the number of cases. The data were analyzed in SPSS software. Results The Mean±SD of nausea in ice group was 1.268±1.9 and in the control group it was 1.787±2.9 and this difference was statistically significant after intervention (P=0.015). The mean of vomiting in ice group was 0.406±0.2 and in the control group it was 0.449±0.266, but this difference was not significant; i.e. the intervention had no significant effect on vomiting (P=0.549). Conclusion Sucking ice bits containing plain water had high effect on reducing nausea caused by chemotherapy but it had no effect on occurrence of vomiting.

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Background and Aim: Topical supplements and vitamins have often been used to accelerate the healing of burn wounds. This study investigated the effects of topical application of vitamin C solution on burn wounds. Methods & Materials: This research was performed on 30 patients with extensive second-degree burns on one or two organs with similar burns. The study subjects were randomly divided into the intervention and control groups. The intervention group received topical application of vitamin C solution in addition to silver sulfadiazine ointment in the burn area; however, only silver sulfadiazine ointment was applied in the burn area in the control group. The wounds were examined and scored on days 1, 3, 7, and 14 using the Bates-Jensen Wound Assessment Tool. The collected data were analyzed in SPSS using repeated-measures Analysis of Variance (ANOVA). Ethical Considerations: This study was approved by the ethics committee of sabzevar university medical sciences. (Code: IR.MEDSAB.REC.1394.60). Results Eighteen of the 30 examined patients were male and 12 were female. Their Mean±SD age and body mass index were 43.03±11.90 years and 27.82±4.08 kg/m2, respectively. Conclusion: The repeated-measures ANOVA data indicated that the study groups were significantly different concerning the final mean scores given to the wounds (P=0.047). In other words, the research groups significantly differed in wound healing; thus, topical application of vitamin C significantly improved wound healing in the study participants.