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In this study, phytochemical screening, antioxidant activity as well as phenolic content in the leaves,twigs and barks of Brucea javanica (L.) were determined using standard phytochemical screeningmethod, DPPH radical scavenging assay and Folin-Ciocalteu reagent method, respectively. Methanolicextracts of these different plant parts were prepared by maceration method. Phytochemical screeningrevealed the presence of flavonoids, terpenoids and tannins in all plant parts. This test also revealed thepresence of alkaloids and saponins in all plant parts except they were absent in the twigs and barks parts,respectively. On the other hand, steroids was absent in all plant parts. DPPH method was used toevaluate the antioxidant properties of the plant parts by measuring the absorbance at 517 nm. Theantioxidant activity was then compared with standard ascorbic acid. Among all parts, methanolic extractof leaves of Brucea javanica (L.) exhibited the highest antioxidant activity at the concentration of 100ppm with 86.19 ± 0.20% inhibition which was comparable with standard ascorbic acid with 97.62 ±0.13% inhibition at the same concentration. The IC50 value of the methanolic extract of leaves was 54.52± 0.16 ppm while the other parts were more than 100 ppm. All plant parts showed IC50 value higher thanthe standard ascorbic acid which recorded IC50 of 9.04 ± 0.09 ppm. The methanolic extract of the leavesalso exhibited the highest total phenolic content which was 105.58 ± 0.21 mg GAE/g extract compared tothe other parts. This result correlated well with the higher antioxidant activity exhibited by themethanolic extract of the leaves. Thus, the leaves part of methanolic extract of Brucea javanica (L.)exhibited the highest antioxidant activity compared to the other plant parts. Keywords: Brucea javanica (L.), simaroubaceae, phytochemical screening, antioxidant activity, phenolic content

Aloe barbadensis leaves and Hylocereus polyrhizus are plants that are easily found in Malaysia. They arecommonly studied for antibacterial activity and how they can benefit the human being. However it is notknown about how the combination of both plants work to become the alternative way of remedies. Theobjectives of this study were to determine the antibacterial, antioxidant, and toxicity of Hylocereuspolyrhizus peels and Aloe barbadensis leaves extracts. The antibacterial activities were evaluatedtowards the bacteria commonly associated with skin infections; which are Staphylococcus aureus,Propionibacterium acnes and Pseudomonas aeruginosa, using Kirby-Bauer Disc Diffusion method. Theantioxidant activity was determined using DPPH assay. The toxicity activity was evaluated by exposingthe extracts towards brine shrimp. As for the results, Aloe barbadensis extracts showed the highestantibacterial activity compared to Hylocereus polyrhizus and the combination of both extracts. For theantioxidant activity and the toxicity test, Hylocereus polyrhizus possessed the best result, where the IC50obtained was 226.397 μg/ml and LC50 was 28588.76 μg/ml (non-toxic). In conclusion, Aloe barbadensis,Hylocereus polyrhizus and the combination of both have the potential to become alternative way asremedies instead of modern medicines.  Keywords: Hylocereus polyrhizus, Aloe barbadensis, antibiotics, antioxidants, toxicity.