Background
There is a high risk of COVID‐19 in kidney transplant recipients (KTRs) because of chronic immunosuppression and severe cytomegalovirus (CMV) pneumonitis.
Case presentation
A case series of 10 KTRs with COVID‐19 in Iran was developed. Participants consisted of two female and eight male patients, aged 46‐68 years old. The data related to clinical laboratory tests, outcomes, diagnosis, and drug treatments were collected. The RT‐PCR confirmed the COVID‐19 infection in KTRs. The assessment of serum biochemical and blood hematological factors showed that there was a strong correlation between COVID‐19 intensity and high serum Cr, BUN, and ALT levels, high CRP concentration, and lower lymphocyte and platelet counts in male KTRs. Ground‐glass opacity (GGO) was the main radiologic pattern visible on both chest radiographs of computed tomography scans. The COVID‐19 and CMV coinfection in KTRs resulted in large‐size kidneys with severe parenchymal echogenicity and hydronephrosis. The combined use of effective antibiotic and antiviral drugs was suitable to prevent COVID‐19 progression in KTRs.
Conclusions
The coincidence of COVID‐19 and CMV in KTRs may potentially increase the mortality risk of patients. The levels of Cr, BUN, ALT, and CRP as well as lymphocytes count in these patients should be continuously controlled.
Introduction: Acne is the most common skin disorder that affects nearly 80% of people in periods of life. Patients with acne often experience depression and anxiety and low selfesteem and generally experience lower quality of life. Therefore, the aim of this study was to evaluate and compare the quality of life in patients with acne vulgaris before and after treatment. Materials and Methods: In this clinical trial, patients with acne referred to the skin clinic were examined. Patients were examined by a clinician and information was collected using a standard questionnaire for determining the severity of acne. After confirming the incidence of acne based on the severity of the disease, they were divided into three groups: mild, moderate and severe. Then, quality of life and self-esteem of patients were assessed using standard questionnaires and then each group received standard pharmaceutical treatment. After the end of the treatment period, the quality of life and self-esteem of patients were re-evaluated. Finally, statistical analysis was performed using SPSS software via t-test and chi square methods. Results: A total of 90 patients were enrolled (30 males and 60 females) with an average age of 26.9 ± 6.1. The results of the study showed that the level of quality of life in the mild, moderate and severe acne group after treatment was significantly higher than the pre-treatment. Also, the level of self-esteem in the mild, moderate and severe groups of the treatment group was significantly higher than the pre-treatment.
Conclusion:The results suggest that treatments have significantly improved the clinical symptoms of acne and increased quality of life and self-esteem in patients. This indicates the importance of acne treatment to improve quality of life and increase self-esteem.
Sulfur mustard is one of the chemical warfare agent. It rapidly reacts with the cutaneous tissues and other tissues, leading to various devastating long-term effects on human health. Mustard-exposed veterans suffer from its chronic skin problems, including itching, burning sensation, and eczema. We aimed to evaluate the protective effects of Myrtus communis L. (myrtle) on chronic skin lesions and quality of life of sulfur mustard-exposed veterans. In this randomized, double-blind clinical trial, 60 sulfur mustard-exposed patients were evaluated. Thirty patients received myrtle essence 5% cream (case group) and 30 patients
HIGHLIGHTS• This is the first study of the protective effects of myrtle cream against sulfur mustard-induces chronic skin complication including; itching and burning sensation.• Myrtle therapy significantly decreased skin lesion symptoms such as excoriation.• Myrtle therapy effectively improved quality of life of the sulfur mustard-exposed veterans.
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