The current study suggests that thymoquinone is able to improve the UUO-induced renal tissue damage. These favorable actions of thymoquinone on UUO model in rat are comparable with the well-known RAS inhibitors captopril and losartan.

AD-MSCs attenuated the CCI-induced mechanical and thermal hypersensitivity. Spinal structural alterations and apoptosis were significantly decreased in the AD-MSCs group. Elevated levels of FGF1 were detected in the spinal tissue.

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Background: Salvia leriifolia have been shown to decrease ischemia-reperfusion (I/R) injury in brain tissues. In this study, the effects of S. leriifolia aqueous and ethanolic extracts were evaluated on an animal model of I/R injury in the rat hind limb.