Objective: To determine the association of Vitamin D deficiency with peripheral neuropathy in patients of type-2 Diabetes mellitus. Study Design and Setting: It was a cross sectional study conducted in a private clinic in Karachi, during a period of three months. Methodology: Total of 70 cases were included according to inclusion and exclusion criteria. Approval was sought from Ethical review committee. Consent was signed from the patients before the data collection. All the patients who were coming to the clinic, 30-75years of age, had history of type 2 diabetes for more than 5 year with HbA1c of 7% or above and had peripheral neuropathy were included. Data was collected in a pre-designed proforma. For entry of data and its statistical analysis SPSS version 20 was used. Results: From the total 70 cases n=41(58.5%) were vit D deficient. Most of the patients with type 2 diabetes with neuropathy were in the age group of 61-75yrs (57%) followed by 46- 60yrs age group (30 %). This study also showed that 30 females (73%) and 11 males (26.8 %) were deficient in vitamin D. Conclusion: Type 2 diabetic patients with vitamin D deficiency were more at risk of developing diabetic peripheral neuropathy (DPN) earlier. It is required to supply vitamin D appropriately for preventing DPN in type 2 diabetes

Objective: To investigate frequency of supernumerary tooth in relation to gender, age and location. Study Design and Setting: Cross-sectional Study was conducted at Mamji Hospital, Karachi from June 2017 to June 2019. Methodology: A total of 2160 patients seen and out of which 45 clinically diagnosed patients of supernumerary teeth were participated in this study. Supernumerary teeth were classified on the basis of location. Descriptive statistics were checked by means of percentages and frequency of all variables. Chi-Square test was applied, P-value < 0.05was considered significant. Results: The total patients were 45 which comprised of 26 male and 19 females with ages ranging from 15 to 60 years. The prevalence of ST was 1.59%, the higher predilection of supernumerary teeth was seen in males than females. The male to female’s ratio was 1.36:1. On the basis of location ST were further classified on Mesiodens, Paramolars and Distomolars category. Of the 45 supernumerary teeth, 36 were had Mesiodens (m= 62.1%, f=37.8%), 5 were Paramolars (m=60%, f=40%) and 3 were Distomolars (m=0, f= 100%). Conclusion: The present study findings showed high prevalence of ST was dominant in males. Present study emphasizes the timely diagnosis and appropriate management of supernumerary teeth to avoid unwanted complications