On epidemiological grounds, Anopheles sinensis has been suspected for many years to be the malaria vector in Korea. Of 7,517 dissections of A. sinensis, one specimen was found for the first time in Korea naturally infected with sporozoites in August 1962. Experimental infection of A. sinensis with Plasmodium vivax had been successfully conducted at earlier date.

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Skeletal muscle injury is one of the most common sports injury, which accounts for ~40% of all sports-related injuries among the elderly. In addition, cases of full recovery from treatment are rare. Although electroacupuncture (EA) is an integral aspect of traditional Chinese medicine, the effects of EA on skeletal muscle fibrosis and the possible underlying mechanism remain unclear. To investigate the effect and potential mechanism of EA on skeletal inflammation, collagen deposition and macrophage function, a skeletal muscle injury model was established by injecting 100 µl cardiotoxin into the anterior tibial muscle of Sprague Dawley rats. The animals were randomly divided into the following three groups: Control, model and EA. The expression of inflammation-related factors (IL-6, IL-4, IL-33, IL-10 and TNF-α) were measured using ELISA. H&E staining, Masson's staining and immunohistochemistry (collagen II, Axin2 and β-catenin) were performed to assess collagen deposition and fibrosis in the muscle tissues. Additionally, immunofluorescence was performed to measure the ratio of M 1 to M 2 macrophages. Western blotting was performed to examine the activity of the TGF-β1/Smad3/p38/ERK1/2 pathway. Compared with that in the control rats, the mental state, such as the degree of activity and excitement, of the model rats deteriorated, with clear activity limitations. Compared with those in the model rats, EA-treated rats exhibited improved mental status and activity, reduced levels of IL-6, IL-4 and TNF-α, reduced collagen deposition and fibrosis, in addition to increased expression of IL-33 and IL-10. This improvement became increasingly evident with prolonged intervention time. EA also promoted the transformation of macrophages from the M 1 into the M 2 sub-type, where the M 1 /M 2 ratio on day 7 was lower compared with that on day 14. Western blotting results showed that compared with that in the model rats, the expression of TGF-β1, MMP-2, MMP-7 and the activation of Smad3 and p38 was decreased in EA-treated rats, whilst the activation of ERK1/2 was significantly elevated. In conclusion, EA can inhibit inflammation and collagen deposition whilst promoting the transformation of macrophages from the M 1 into the M 2 sub-type. The underlying mechanism was found to be associated with TGF-β1/Smad3/p38/ERK1/2 signaling.

Based on severe weather reports, surface precipitation observations, surface routine observations, and the European Center for Medium-Range Weather Forecasts ERA5 reanalysis dataset during the warm seasons (May–September) of 2011–2018 over North China, this paper analyzes the statistical characteristics and environmental conditions of three types of severe convective events. Results are compared between events with different altitudes (i.e., mountains and plains), severities (i.e., ordinary and significant), and months. Hail and thunderstorm high winds (THWs) are more common over the mountains whereas short-duration heavy rainfall (SDHR) is more frequent over the plains. The occurrence frequency of severe convective events exhibits distinct monthly and diurnal variations. Analyses of the environmental parameters provide reference for the potential forecasting of severe convective events over this region. Specifically, the 850–500 hPa temperature lapse rate (LR85), pseudo-equivalent potential temperature at 500 hPa (thetase500), and precipitable water (PW) are skillful in distinguishing hail and THW environments from SDHR environments, and thetase500 is useful in discriminating between hail and THW environments. The convective environments over the plains are characterized by significantly higher (lower) PW (LR85) compared with mountains. The skill of these parameters in forecasting the severity of the convective hazards is limited. Probability distributions in the two parameters space indicate that the occurrence of significant hail requires both higher most unstable convective available potential energy (MUCAPE) and stronger 0–6 km bulk wind shear (SHR6) compared with ordinary hail. Compared with ordinary THWs, the significant THWs over the mountains depend more on the SHR6 whereas those over the plains rely more on the MUCAPE. The significant SDHR events over the plains tend to occur under a variety of instability conditions. The thermodynamic parameters (i.e., MUCAPE, thetase500, and downdraft convective available potential energy), and PW are significantly higher in July–August, whereas the LR85 and vertical wind shear are apparently higher in May, June and September.

From 17 to 22 July 2021, a series of disastrous rainstorms appeared within Henan Province and its surroundings, which rendered 398 dead/missing and a direct economic loss of up to ∼114 billion Yuan. This event was named as the “21.7” Henan torrential rainfall event (TRE), and it could be divided roughly into three stages according to the precipitation features and dominant weather systems. This study mainly focused on the development and maintenance mechanisms of a long-lived (72 h) quasi-stationary mesoscale vortex that governed the earlier stage of the “21.7” TRE. Main results are as follows: 1) the mesoscale vortex formed/maintained in a favorable environment which was characterized by the South-Asia-high associated divergence in the upper troposphere, and the relay transport of relatively cold air by the trough and high-pressure system in the middle troposphere. 2) the vertical stretching due to lower-level convergence and the upward transport of cyclonic vorticity by ascending motions served as the first and second dominant factors for the mesoscale vortex’s rapid development and long-time maintenance, whereas, the import/export transport of anticyclonic/cyclonic vorticity into/from the vortex’s central region and the tilting effects were mainly detrimental for the vortex’s development/maintenance. 3) the air particles that formed the mesoscale vortex mainly came from the levels below 1,500 m, within the regions in lower latitudes. The air particles experienced notable precipitation before the formation of the mesoscale vortex, which contributed to the vortex’s formation through latent heat release.