Central Odontogenic Fibroma (COF) is a rare, benign neoplasm of mesenchymal origin that makes up less than 5% of odontogenic tumors commonly found in women in ratio 2.8:1. For many years there was considerable confusion concerning the criteria by which the lesion should be diagnosed and as a result, a verity of different conditions were being reported as odontogenic fibroma (OF). In this article reporting a case of COF (Epithelium Rich-type) in the maxilla radiographically presented as a well-defined radiolucent and radiopaque lesion retarding the first premolar from erupting plus reviewing the literature about COF including its variants.
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