Development of interactive multimedia is an alternative solution for learning in elementary schools that are not optimally delivered through direct observation, more precise for science learning on water cycle material that has difficulty delivered in the classroom to facilitate the achievement of basic competence that has the same achievement with 21st century competence that is analytical thinking ability. Based on this urgency, this research has a purpose to know the procedure of developing interactive multimedia learning that can improve analytical thinking ability on the water cycle material and know the effectiveness of interactive multimedia developed to improve analytical thinking ability of the elementary student. The method is research and development of Lee and Owens model (assessment and needs analysis, design, development and implementation, and evaluation). The research result was: (1) interactive multimedia learning to improve analytical thinking ability on water cycle material reached standard on validation of three experts (material, media, and language) and four practitioners (all validators in each aspect or 100% validators approve interactive multimedia product to be implemented in learning) as well as student review in the limited group trial of interactive multimedia developed is positive (the percentage gain of each aspect is in excellent interpretation), (2) interactive multimedia learning developed effectively to improving analytical thinking ability of elementary school student.