An In(OTf) 3 -catalyzed domino reaction involving sequential oxidative ring opening of aziridines by using the solvent dimethyl sulfoxide and intramolecular Michael addition has been developed for the modular synthesis of 2-aminoindanone compounds by the formation of one new CO bond and one new C−C bond. The notable feature of this strategy includes broad substrate scope, excellent trans-diastereoselectivities, highly functionalized products, and mild conditions. The catalyst In(OTf) 3 plays an important role in the formation of the indanone ring.

A rhodium(ii)-catalyzed tandem reaction involving O–H insertion of N-sulfonyl 1,2,3-triazoles and Michael addition has been described. A series of 2-amino-1-indanones were afforded in acceptable to good yields with high diastereoselectivities.

A type of 2,2‐disubstituted N‐sulfonylaziridines bearing OTBS groups and aryl groups at two different substitutions of the aziridine ring has been prepared. Based on them, a stepwise strategy involving ring opening of aziridines and C−H activation/cyclization has been developed for the general synthesis of spiroindoline pyrans and spiroindoline furans.

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