Polyacrylic acid (PAA)/calcium carbonate (CaCO 3 ) nanoparticles (NPs) were synthesized via a simple and novel strategy. The asprepared PAA/CaCO 3 NPs not only exhibit ultrahigh doxorubicin (DOX) payload (1.18 g of DOX per g of NPs) but also possess pHsensitive drug release properties. In vivo experiments show that the DOX-loaded PAA/CaCO 3 NPs display a significant antitumor effect (76% average inhibition rate relative to the control group) without distinct side effects. Therefore, PAA/CaCO 3 NPs are promising candidates for cancer therapy as efficient drug delivery vehicles.
he emergence and prevalence of drug-resistant bacteria caused by overuse of antibiotics pose new challenges to the treatment of bacterial infections. In this work, the hollow mesoporous CuO nanozymes (HM-CuO...
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