Background and Aim: Long-term hypertension proceed to development of atherothrombotic disease and it's a major healthcare problem worldwide. Platelets and neutrophils play an important role in Cardiovascular (CV) events and development of atherothrombotic disease. Recently, Neutrophil/lymphocyte Ratio (NLR) and Platelet/lymphocyte Ratio (PLR), which can be easily calculated from the differential blood count, have been proposed as novel systemic inflammation-based markers predictive of thrombotic events. The aim of the present study was to explore the association between NLR and PLR with hypertension and as an indicator of cardiovascular risk. Methods: It's a cross sectional study. 50 Hypertensive patients aged 40-60 years, males and females with the history of Previously diagnosed hypertension >1 year duration or taking anti-hypertensive medications with blood pressure Systolic BP > 140 mm Hg, Diastolic BP > 90 mmHg were taken as study group. 50 normotensives aged 40-60, males and females with Systolic BP < 140 mmHg, Diastolic BP < 90 mmHg were taken as control group, who were matching socioeconomically with study group. A detailed history and physiological parameters were taken. Blood pressure was measured via auscultatory method using sphygmomanometer. Under aseptic precautions, 3 ml of venous blood samples were collected and analysed. Results: Neutrophil to Lymphocyte Ratio (NLR) was significantly higher (p<0.01) in study group. Platelet to Lymphocyte Ratio (PLR) was also higher in study group but statistically not significant (p>0.05). Conclusion: Hypertensives with higher NLR have greater risk for athero-thrombotic and atherosclerotic events.

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Background: Young adults are more attracted toward fast food, alcohol, and sedentary lifestyles. Previous study shows that peak expiratory flow rate (PEFR) correlates better with height in males and weight in females. Body mass index (BMI) is one of the main factor that affect PEFR values. PEFR, a pulmonary function test is routinely used to confirm the diagnosis of the respiratory disease. Aim and Objectives: This study was conducted to evaluate PEFR values in male and female young adults in underweight, normal, overweight, and obese categories of weight status. Materials and Methods: The study was conducted in four groups. 40 participants in each group, includes males (20) and female (20) young adults. The groups were divided according to BMI values, underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (>30). Data were taken and calculated 2 h post lunch after relaxing for 15 min in the afternoon. In the sitting position, at the same time of the day, PEFR values were measured using Wright’s Peak Flow Meter. Results: We found significantly high PEFR values in males as compare to females in the category of underweight (<0.01), normal (<0.05) and overweight (<0.05). The study also shows positive correlation between BMI and PEFR in underweight male and females, normal males, overweight females, and obese females, which is statistically non-significant, except in obese males. Conclusion: We concluded that male have high PEFR values than female as there are differences in their body build-up and low PEFR values in underweight and obese young adults as they have low body fat and reduced expansion of lungs, respectively.