Depression is a widespread mental illness. About 264 million people worldwide are affected by depression at all ages. More women than men suffer from depression. Depression diagnosis includes at least two weeks of either low mood or anhedonism and 4 or more other symptoms such as shift of appetite or weight, insomnia or hypersomnia, psychomoting agitation, or delayed, lack of control, inability to focus, feelings of insignificance or excessive weight, according to Diastic and Statistical Manual, Fifth Edition (DSM-5). The treatment of moderate-serious depression can be a successful form of antidepressants. Selective serotonin reuptake inhibitors (SSRIs) are the most widely used medications for depression, that target the monoaminergic system, but have some drawbacks, such as delayed initiation of action. The N-methyl d-aspartate receptor, or antagonist ketamine, was very interested in psychiatric studies, due to its rapid action against depression, in particular in patients who suffered from extreme treatment-resistant depression (TRD). The clinical effectiveness of ketamine in TRD has been addressed in this review with reliance on RCT data.

Takayasus arteritis primarily affects young women. Takayasu arteritis (TA) is a type of primary systemic vasculitis mainly affecting the medium and large arteries. The signs and symptoms are due to systemic inflammation or ischemia of an organ or limb and include angiodynia, claudication, peripheral pulselessness, murmurs, ischemic stroke, myocardial infarction and severe systemic arterial hypertension. The disease tends to affect more women than men.The current case of Takayasu arteritis type V focuses on a 21 year female who complained of cold, cough, fever, facial puffiness since 2 months, along with bilateral renal artery stenosis, and resistant hypertension.

The computer machine Artificial Intelligence (Al). Which aims to emulate human intelligence, has become highly active and is introduced into many areas including medicine. The area of Al implementation for better test quality and patient treatment includes stroke medicine. The Stroke is the second leading cause of death, with severe, long term disability. Stroke is a sudden cortical disappearance due to lack of oxygen, narrowing of the blood stream or an inability to provide the consciousness with the pathway. The forms of stroke are ischemic hemorrhagic and acute ischemic. The death risk will continue to rise, according to the World Health Organization, with the next year’s stroke. Various experiments have been undertaken to diagnose stroke disorders. An artificial intelligence is the method for the detection and application deep learning for stroke and its forms.  Keywords: Artificial Intelligence, Machine learning, Stokes, Stroke Prediction, Stroke Disease, Stroke AI technology.

The mammalian purpose of rapamycin (mTOR) has been found to gather insights into their essential role in pathogenesis of breast cancer. hMany clinical trials have shown that the mTOR everolimus inhibitor can enhance patient results for several sub-types of breast cancer, including harmone receptor-positive, human-epidermal growth factor receptor-negative metastatic disease that has developed, followed by endocrine therapy. This analysis summarises the results of clinical studies that support the efficacy of everolimus in metastatic breast cancer, and discusses several new research directions for everolimus.