Polyindole-based hybrid composites are being recognized as a promising candidate to be used in energy storage field along with other conjugated organic polymers. Polyindoles themselves are affected with low electrical and electrochemical conductivity; nevertheless, high redox activity, tunable electrical conductivity, significant thermal stability, slow degradation rate, and possible blending property give them upper hand to be used as a good contender. Certain factors viz. electrolyte, concentration, morphology, pH, temperature, etc., are major components affecting performance of Polyindole and its composites. This assessment recapitulates the position of Polyindole and its hybrid composite to be used as energy harvest material; in addition, this evaluation also pronounces the future aspect of the hybrids.

From nanopharmaceutics to renewable energy, silver nanoparticles (AgNPs) present innumerable applications in the contemporary era. However, the associated toxicity to the biosystems limits their application. Effective utilization of AgNPs, therefore, requires their surface conjugation with biologically benevolent moieties that enhance the bio-acceptability of silver-based nanosystems, and supplementary functionalities for further extension of their unique applications. The clinical importance of AgNPs was established long ago, but their clinical utilization has been explored only recently with the phenomenon of bio-conjugation. The biomolecule-conjugated AgNPs present operable solutions for tedious clinical complications of the present era, such as multidrug resistance, designing of pharmaceuticals with improved bioavailability, superior drug delivery vehicles and in situ bio imaging of important metabolites that utilize the biomolecule-anchored surface engineered AgNPs. This review epigrammatically discusses some interesting clinical applications of surface conjugated AgNPs with biomolecules such as peptides, nucleic acids, amino acids and antibodies in the current nanopharmaceutical paradigm.

Utility of silver metal in antimicrobial therapy is an accepted practice since ages that faded with time because of the identification of a few silver resistant strains in the contemporary era. A successive development of antibiotics soon followed. However, due to an indiscriminate and unregulated use coupled with poor legal control measures and a dearth of expertise in handling the critical episodes, the antibiotics era has already seen a steep decline in the past decades due to the evolution of multi-drug resistant 'superbugs' which pose a sizeable challenge to manage with. Due to limited options in the pipeline and no clear strategy in the forefront, the aspirations for novel, MDR focused drug discovery to target the 'superbugs' arose which once again led to the rise of AgNPs in antimicrobial research. In this review, we have focused on the green routes for the synthesis of AgNPs, the mode of microbial inhibition by AgNPs, synergistic effect of AgNPs with antibiotics and future challenges for the development of nano-silver-based therapeutics.

Background: Carbon-based metal oxide nanocomposites are always been the prime material for study in the field of energy storage due to their rich abundance, low toxicity, high surface area, electrical conductivity and diverse oxidation states. Methods: In this direction, novel zirconia/graphene oxide (ZrO 2 /GO) nanocomposites are fabricated on the surface of 316 stainless steel for studying their specific capacitance and power performance. ZrO 2 and GO in varying mass ratio (1:1, 1:2, and 2:1) were used to fabricate the electroactive material. The physical interaction between the two was determined by Fourier transform-infrared, X-ray diffraction and scanning electron microscopy. TG-DTA-DG informs about the exhibited thermal property by the variants. The cyclic voltammetry was done to study the specific capacitance of the electroactive materials with reference to Ag/AgCl at scan rate (V/s) ranging 0.15-0.001 in 1.0 M KOH. The specific capacitance of ZrO 2 was found to be 17.13 Fg −1 at 0.001 Vs −1. The representative (nanocomposite) NC-II shows the maximum specific capacitance of 299.26 Fg −1 at similar rate of scan with power density of 59.40 W/kg. Conclusion: The nanocomposites show comparable level of charge-discharge behavior with long-term cycleability, suggesting that fabricated ZrO 2 /GO nanocomposite electrodes are promising candidate for the high-performance energy storage devices.