No abstract

Currently accepted methods for the determination of antibiotic susceptibility are based upon the visual estimation of bacterial growth in the presence of antibiotics. Techniques employed include the use of antimicrobial discs, agar well diffusion, agar dilution, microtitration, and serial broth dilution (1,5,6). The serial broth dilution methods, which are generally considered the reference to which other methods are compared (4), require 24 to 48 hr to complete in most laboratories.We have previously described an automated radiometric method for the detection of bacterial growth and its clinical application in blood cultures (2, 3). The present report describes the use of this principle for rapid automated quantitative measurement of antibiotic effect on bacterial growth.MATERIALS AND METHODS The antibiotics tested, with the bacterial species they were tested against given in parentheses, were

Abstract• A case of fibromuscular dysplasia (FMD) of the posterior cerebral artery with classic presumptive angiographical findings is presented, and the literature pertaining to FMD of the cervical arteries is reviewed. The focal neurological findings and characteristic changing pattern seen on sequential brain scans clearly associate the presence of this lesion to cerebral infarction. Various proposed etiologies and the characteristic pathological and radiological appearance of FMD are discussed. Emphasis is placed on the potential for this lesion to produce significant clinical sequelae, and on the relationship between FMD and the presence of intracranial aneurysms. The natural history and proper treatment remain uncertain; however, the general impression is for slow progression of existing lesions associated with development of new lesions in other locations. Additional Key Words intracranial aneurysms cerebral infarction in young adultarterial occlusion

No abstract

No abstract