Objective: To estimate the prevalence of multiple risk factors for cardiovascular diseases (CVD) among manufacturing employees in Sousse, Tunisia and to determine factors associated with this clustering. Methods: A cross-sectional study was carried out to estimate the prevalence of CVD risk factors in workplaces and their clustering. We used data from a workplace-based intervention which took place in six companies of the governorate of Sousse in Tunisia, Tunisia. Results: A total of 2113 employees were surveyed. The prevalence of having four or five risk factors tended to be higher among male employees, those with higher education level and those who were part of managerial staff. Conclusion: Screening and targeted health promotion initiatives should be launched in worksite targeting the modifiable factors to avert the excessive risk for CVD.

Methods Newly diagnosed 252 consecutive PD patients were included and followed as part of an ongoing PD registry. PD was diagnosed according to the United Kingdom brain bank diagnostic criteria. 79 PD patients fulfilled the DSM-IV criteria for major depression. The UPDRS motor score was checked at the best "on" period to assess the clinical severity of PD. We compared the clinical data between depressive (DP, n¼79) and non-depressive (NDP, n¼173) groups. Results The prevalence rate of depression in PD was 31.3% in this study. There was no difference in age (DP: 62.362.5, NDP: 59.862.7 yrs), age of disease onset (DP: 52.063.7 yrs, NDP: 54.763.8 yrs), UPDRS motor scores (DP: 36.265.6, NDP: 33.863.7) and Hoehn and Yahr stage (DP: 3.3460.52, NDP: 2.9160.63) between two groups. Conclusion There was no significant difference in clinical features between DP and NDP groups in this study. These results suggest that depression in PD is not influenced the severity of motor symptoms and that non-dopaminergic neurotransmitters, such as norepinephrine and acetylcholine, at least associated with the pathophysiology of depression in PD. Throughout the world, and particularly in Tunisia, children are becoming overweight and obese at progressively younger ages. Our purpose was to evaluate the effects of a school intervention program to promote healthy nutrition and physical activity among adolescents, in terms of behaviours and intention. Methods It was a quasi experimental intervention study with two groups: control and intervention group with pre-post evaluation of nutrition and physical activity intention and behaviour in each group. The target population was composed with students aged 12e16 years schooled in colleges of Sousse in Tunisia. To evaluate the intervention, a sampling was used to include 2200 students who participated to the questionnaire. All the students of intervention group received a standardised program with information about healthy nutrition and physical activity. An Arabic pre-tested and auto-administered questionnaire was used to assess nutrition and physical activity intention and behaviour before and after the intervention. Results The intervention group's posttest intention and behaviour were significantly higher than the control group's posttest. Concerning "healthy behaviours", in the intervention group, children improved significantly their vegetable intake. It passed from 45.4% to 56.8% (p<0.001). The proportion of children who practice 5 days per week physical activity for at least 30 min a day increased significantly from 23% to 44% (p<0.001). Conclusion School based intervention to promote healthy diet and physical activity is benefit and important at the middle age to prevent obesity and cardiovascular disease risk factors. SP1-46