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of the skin. Five per cent, sterile boric acid ointment is a good dressing covered by sterile gauze pad and bandage, or 10 per cent, sodium bicarbonate ointment.The eyes are washed with solution of boric acid and covered, and the lids protected for some time with bland yellow mercuric oxid ointment and fear of further injury dispelled. Later dusting powder of bismuth and zinc oxid, or of zinc stearate will prove satisfactory for abraded skin areas.Dugouts and holes where a person is likely to sit are to be suspected and carefully evacuated by an attendant wearing oil canvas protection. Then chlorinated lime is scattered in places suspected. Articles of salvage and waste should always be held under suspicion of being contaminated. The clothing is soaked in several changes of water at 70 C. Instead of . strong alkaline remedies, potassium permanganate, 0.05 per cent, solution, is recommended, or a 0.1 per cent, zinc chlorid, and between the fingers or folds of the , scrotum, a weak silver nitrate solution. In advanced respiratory cases, oxygen inhalations are used.Owing to the censorship, the photographic reproduction of many interesting cases is not permissible. These cases should be given careful attention, and after treatment one need not necessarily excuse patients with mild skin burns from duty.

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We have employed two essentially different methods for obtaining insulin from the excised pancreas of various animals : First, extraction with different media after maceration of the pancreases; and secondly, perfusion of the intact organs with various solutions. In a series of twenty-nine perfusions done during the past ten months we have purposely varied the many factors involved-such as the composition of the perfusion fluid. the temperature of the chamber containing the organs, the rate of perfusion, volume of perfusate, time of perfusion, and perfusion pressures-within wide limits in order to select tke simplest method which is efficient. A comparative analysis of these various factors leads us to conclude that the simplest efficient method is that of continuous gravity perfusion with 0.2 per cent. HCl at or somewhat above body temperature (37C. to 45C.), under a pressure of 120 mm. Hg, for a period of one hour.In determining the potency of preparations we have used a dose of two cubic centimeters of final concentrated product administered subcutaneously to normal rabbits. Blood is taken from the ear veins before the injection and again two hours after the injection. A drop of 70 milligrams in blood sugar is taken as a rabbit unit and on this basis the yield in rabbit units per kilo of pancreas is calculated.The perfusion method appears to give about three times as much insulin (estimated as Rabbit Units) per kilo as is obtained by the extraction methods employed and gives a product which is much more easily and quickly concentrated because of the absence of the large amounts of protein and extraneous material which were obtained when extraction processes were used.

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