Background and Objectives: Mineral nanoparticle synthesis via green chemistry is ‎considered a novel ‏procedure ‎that ‎has been introduced into some ‏‎‎industries and medical fields. This ‎paper aimed to focus on ‏synthesized gold ‎nanoparticles ‎‎‎‎(‎AuNPs‎) prepared via green chemistry and ‎their usage in the ‏treatment of cutaneous ‎candidiasis.‎‎ Materials and Methods: This study was performed on the green synthesis of AuNPs using olive leaf extract as a reducing ‎agent‎. The ‎UV‎ visible spectroscopy, X-ray diffraction, and atomic force microscopy techniques ‎were used to detect ‏the concentration of the prepared AuNPs‎. ‎The agar gel diffusion method was used to test ‏the ‎antifungal activity of the ‎‎prepared AuNPs in vitro. ‏Antifungal efficacy of the AuNPs in vivo ‎was tested by the ‎induction of‎‎ cutaneous ‎candidiasis in mice‎. ‎This research was conducted on four groups of mice‎. Groups 1 and 2 were used to evaluate the effectiveness of the AuNPs suspension ‎and ‏Nystatin ointment in the treatment ‎of clinical infection, respectively. Groups 3 ‎and ‎4 were the infected ‎and the non-infected control groups, respectively.‎ Results: Based on the findings, the AuNP synthesis using olive leaves was ‎a suitable and ‎secure method. Moreover, it was found that the AuNP concentration of 40.77 ng‏\‏ml represented the minimum ‎inhibitory concentration for the ‎inhibition of the Candida albicans. The prepared AuNPs were more effective than Nystatin ‎in the ‏treatment ‎of cutaneous candidiasis.‎‎ Conclusion: Preparation of AuNPs via green chemistry using olive leaves as a reducing ‎agent is a ‏safe ‎and easy procedure that can be performed to produce AuNPs. In this study, the AuNPs ‎displayed antifungal ‏activity ‏both in vitro and in vivo.

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Non-Typhoidal Salmonellosis (NTS) is a form of salmonellosis that infect human from host-non adapted serotypes of salmonella, these salmonella strains are distributed in the environment, water and food via warm blooded animals causing gastroenteritis illnesses mostly, accompanied by high antibiotic resistance profile. In Najaf, camel meat considered one of the most used meat for human consumption. Yet, studies on distribution of salmonella and antibiotic resistance is scarce. In this research, (32) isolates of salmonella were isolated from camels in the province of Al-Najaf, using ordinary bacteriological methods, according to internationally known protocols for the cultivation and characterization of this bacteria. Then, all positive isolates subjected by antibiotic sensitivity test. The results showed a very high multidrug resistance profile was noticed among the isolated salmonella.