During pregnancy, cutaneous and appendageal alterations manifest and may cause concern in the subject. The nails may be affected by pregnancy. This study investigated the frequency and nature of nail changes occurring during pregnancy in 312 healthy, 18-40-year-old pregnant women in gestation weeks 16-40. After a routine obstetric examination at the obstetrics and gynecology clinic at the study institution, all subjects submitted to an examination of all fingernails and toenails. Only nail alterations that had developed during pregnancy were recorded. Any nail changes that had occurred before the start of gestation were not considered. Data were presented as percentages. The Shapiro-Wilk and chi-squared tests were used to make categorical comparisons. A P-value of < 0.05 was considered to indicate statistical significance. No nail pathologies were detected in 116 (37.2%) of the 312 subjects. The most commonly found nail change was leukonychia (24.4%). Ingrown toenail (9.0%) and onychoschizia (9.0%) represented the second most common nail changes. Rapid nail growth and subungual hyperkeratosis were observed in 6.7% and 4.2%, respectively, of subjects. When the alterations were evaluated according to gestational age, the most common nail pathology was leukonychia at both 14-28 weeks (16.3%) and 29-42 weeks (27.4%) of pregnancy. Leukonychia, onychoschizia, onycholysis, and brittle nail pathologies were frequently observed at 29-42 weeks of pregnancy (P = 0.047). A large proportion of nail changes that occur during pregnancy are benign and do not require treatment. However, these changes may cause significant cosmetic stress in women.

BackgroundBackground: Demodex mites are acari that reside in the pilosebaceous unit of the skin and have been associated with skin disorders.ObjectiveThe objective of this study was to investigate the prevalence of Demodex folliculorum (D. folliculorum) mites in polycystic ovary syndrome patients as well as to examine the relationship between Demodex infestation and the presence of acne and oily or dry skin types in polycystic ovary syndrome patients.Methods41 polycystic ovary syndrome patients and 47 non-polycystic ovary syndrome control subjects were enrolled in the study. polycystic ovary syndrome was diagnosed according to the revised 2003 ESHRE/ASRM polycystic ovary syndrome Consensus Workshop Group diagnostic criteria. Microscopic examination of D. folliculorum mites was carried out by standardized skin surface biopsy. The result was considered positive when there were more than 5 mites per cm2.ResultsD. folliculorum was positive in 53.7% of the polycystic ovary syndrome patients and 31.9% of the non-polycystic ovary syndrome group (p=0.052). Demodex positivity was significantly associated with acne (p=0.003) and oily skin (p=0.005) in the polycystic ovary syndrome patients but not in the controls.Study limitationOur study is limited by the relatively small number of subjects and the observational nature of the study design.ConclusionDemodex mites might have a role in acne pathogenesis in patients with polycystic ovary syndrome. Anti-Demodex treatment may increase the response to treatment of acne. Further studies are indicated.

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Kolorektal kanserlerin erken evrede belirlenmesi, prognozun iyileştirilmesindeki en önemli kısımdır. Bunun yolu etkili tarama programlarından geçmektedir. Gaitada gizli kan testi tarama yöntemlerinin başında gelmektedir. Bu çalışmada endoskopi ünitemizde gaitada gizli kan testi pozitifliği nedeniyle kolonoskopi yapılan hastalarda kolonoskopik bulguları değerlendirmeyi, polip sıklığını, histopatolojik tiplerini ve kolorektal malignite sıklığını saptamayı amaçladık. Materyal ve Metod: 2018 Aralık ve 2019 Temmuz ayları arasında gaitada gizli kan pozitif olup etiyoloji araştırılması nedeniyle kolonoskopi yapılan hastalar çalışmaya alındı. Kolonoskopi uygun hazırlık sonrası terminal ileum da değerlendirilecek şekilde uygulanmıştı. Hastaların yaş, cinsiyet, anamnez bilgileri, kolonoskopi ve patoloji sonuçlarına dosya bilgileri araştırılarak geriye dönük olarak ulaşıldı. Bulgular: Bu sürede gaitada gizli kan pozitifliği nedeniyle 70 hastaya kolonoskopi yapılmıştı. Hastaların 36'sı (%51) erkek, 34'ü (%49) kadındı. Erkeklerin yaş ortalaması 50,1±14,8, kadınların yaş ortalaması 54,6 ± 13,9 idi. Olguların 13'ünde (%19) adenomatöz polip, 4'ünde (%5,7) adenokarsinom ve birinde (%1,4) malign melanom tespit edildi. Polip tespit edilen 7 erkek ve 6 kadın hastanın yaş ortalamaları 61,5±9 idi. Poliplerin %76'sı sol kolonda, malignitelerin %80'i rektosigmoid kolonda idi. Olguların %74'ünde gaitada gizli kan pozitifliğini açıklayacak bir patoloji saptanmamıştı. Poliplerin tamamı kolonoskopik yöntemlerle başarıyla çıkarılmıştı. Sonuç: Gaitada gizli kan pozitifliği nedeniyle kolonoskopi yapılan olguların %7'sinde kolorektal malignite ve %19'unda adenomatöz polip saptanması gaitada gizli kan testi pozitifliğinin önemini göstermektedir. Tarama programları sayesinde kolorektal kanserler ve prekanseröz lezyonların erken teşhis edilip, sağ kalım oranlarının artabileceği görülmektedir.

Psychiatric symptoms, perceived social support, coping styles, and dyadic adjustment in pregnant women with hyperemesis gravidarum Objective: Hyperemesis gravidarum (HG) is a condition with severe nausea and vomiting, which is seen in 0.3-2% of pregnancies. In addition to biological factors, psychosocial factors were also reported to play a role in the development of HG. However, the impact of psychosocial factors in HG has not been elucidated yet. In this research, we aimed to investigate psychiatric symptoms in patients with HG and their relationships with perceived social support, coping styles, and dyadic adjustment. Method: Forty-eight women with HG hospitalized in the Obstetrics and Gynecology Inpatient Unit and 48 healthy pregnant women consulted to the Obstetric Outpatient Unit for their routine obstetric control were recruited for the study. The subjects were evaluated with sociodemographic form, Symptom Check List (SCL-90-R), Multidimensional Scale of Perceived Social Support (MSPSS), Ways of Coping Scale (WCS), and Dyadic Adjustment Scale (DAS). Results: All sociodemographic variables except nausea and vomiting history in previous pregnancies were similar in both groups. All subscales and global symptom index scores of SCL-90-R were higher; optimistic and submissive subscale scores of WCS were lower, satisfaction, consensus and total scores of DAS were higher in HG group (p<0.05). Conclusion: Psychiatric symptom levels are higher in women with HG compared to the controls. No difference for previous psychiatric history among groups shows that previous psychiatric history is not a predictor for HG. The psychiatric symptoms in HG is self-limiting and possibly due to HG symptoms. Psychosocial factors such as perceived social support, coping styles, and dyadic adjustment may contribute to the psychiatric symptoms. Keywords: Coping styles, dyadic adjustment, hyperemesis gravidarum, perceived social support, psychiatric symptoms ÖZET Hiperemezis gravidarumu olan gebelerde ruhsal belirtiler, stresle başa çıkma tarzları, algılanan sosyal destek ve çift uyumu Amaç: Hiperemezis gravidarum (HG), şiddetli bulantı-kusma ile giden ve gebelerin yaklaşık %0.3-2'sinde görülen bir tablodur. Biyolojik etkenler yanında psikososyal etkenlerin de HG gelişiminde rol oynayabileceği bildirilmiştir. Fakat, HG'de psikososyal etkenlerin rolü tam olarak gösterilememiştir. Bu çalışmada HG ile ruhsal belirtiler ve bu belirtilerin algılanan sosyal destek, stresle başa çıkma tarzları ve çift uyumu arasındaki ilişkisini değerlendirmeyi hedefledik. Yöntem: Kadın Hastalıkları ve Doğum Kliniği'nde HG tanısı ile yatırılan 48 gebe ile hastanenin Kadın Hastalıkları ve Doğum polikliniğine rutin doğum öncesi kontroller için başvuran 48 sağlıklı gebe çalışmaya alındı. Denekler, sosyodemografik form, Belirti Tarama Listesi (SCL-90-R), Çok Boyutlu Algılanan Sosyal Destek Ölçeği (ÇBASDÖ), Stresle Başaçıkma Tarzları Ölçeği (SBTÖ) ve Çift Uyum Ölçeği (ÇUÖ) ile değerlendirildi. Bulgular: Bulantı kusma öyküsü dışında tüm sosyodemografik değişk...