This study aimed to analyze the relationship between gallstone and histopathological changes of gallbladder mucosa among patients with gallstones. Samples consisted of 38 patients with gallstones who were performed elective cholecystectomy either by laparoscopy or by laparotomy on them. Gallstones were analyzed macroscopically to determine the types of stones. Specimens of resected gallbladders were examined histopathologically to obtain the changes of gallbladder mucosa. The results showed that macroscopical analysis resulted in three types of gallstones: cholesterol stone (76.3%), pigmented stone (21.1%), and mixed stone 2.6%). Histopathologically, all resected speciments showed changes of gallbladder mucosa in the forms of chronic inflammation or associated with hyperplasia. There was no incidental cases of gallbladder cancer. An analysis of the relationship between the types of stones and the histopathological changes of gallbladder mucosa with the chi-square test showed an X2 value of 0.483 and a P value of 0.392. Conclusion: In this study, there was no relationship between the types of gallstones and the histopathological changes of gallbladder mucosa among patients with gallstone.Keywords: gallstone, cholecystectomy, gallbladder mucosaAbstrak: Penelitian ini bertujuan untuk menganalisis hubungan batu kandung empedu dengan perubahan mukosa kandung empedu pada pasien dengan batu kandung empedu. Sampel terdiri dari 38 pasien batu kandung empedu yang menjalani operasi elektif kolesistektomi, baik secara laparoskopik maupun secara terbuka. Batu kandung empedu dianalisis secara makroskopik untuk menentukan jenis batu. Spesimen reseksi kandung empedu diperiksa secara histopatologik untuk melihat ada tidaknya perubahan mukosa kandung empedu. Dari hasil analisis batu secara makroskopik didapatkan 3 jenis batu kandung empedu, yaitu batu kolesterol (76,3%), batu pigmen (21,1%), dan batu campuran (2,6%). Semua spesimen reseksi kandung empedu diperiksa secara histopatologik dan menunjukkan perubahan mukosa kandung empedu berupa radang kronis dan hiperplasia. Tidak terdapat penemuan secara insidental terhadap kanker kandung empedu. Analisis hubungan antara jenis batu kandung empedu dan perubahan mukosa kandung empedu dengan uji chi-square mendapatkan X2 = 0,483 dengan P = 0,392. Simpulan: Dalam penelitian ini tidak didapatkan hubungan antara jenis batu dan perubahan mukosa kandung empedu pada pasien dengan batu kandung empedu.Kata kunci: batu kandung empedu, kolesistektomi, mukosa kandung empedu
This study aimed to observe the influence of chocolate per oral aministered 6 hours post laparotomy in shortening the duration of postoperative ileus in patients with appendicitis perforata. Participants were 34 patients with perforated appendicitis who had laparotomy performed on them; 17 patients were given chocolate per oral meanwhile the others were controls. This grouping was obtained by using stratified random sampling with double blind technique. The results showed that chocolate administration 6 hours post laparotomy could shorten the duration of postoperative ileus with an average of 8,8 hours. This effect was significant for the occurence of the first flatus, but not for the first peristalsis and defecation.Keywords: postoperative ileus, perforated appendicitis, chocolateAbstrak: Penelitian ini bertujuan untuk mengamati pengaruh coklat per oral yang diberikan sejak 6 jam pascaoperasi dalam mempersingkat durasi ileus pascaoperasi pada pasien yang menjalani laparotomi atas indikasi apendisitis perforata. Partisipan ialah 34 pasien apendisitis perforata yang menjalani laparotomi; 17 di antaranya diberi coklat dan 17 lainnya berperan sebagai kontrol. Pengelompokan dilakukan secara acak dengan teknik buta-ganda. Hasil penelitian memperlihatkan bahwa pemberian coklat sejak 6 jam setelah laparotomi dapat mempersingkat durasi ileus pascaoperasi hingga rata-rata 8,8 jam. Efek ini terlihat secara bermakna dalam mempercepat terjadinya flatus pertama (rata-rata lebih cepat 8,8 jam), namun tidak dalam hal bising usus pertama dan buang air besar pertama.Kata kunci: ileus pascaoperasi, apendisitis perforata, coklat
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