Preeclampsia is the most common medical complication of pregnancy associated with increased maternal and infant mortality and morbidity. Reduced serum magnesium level is found to be associated with elevated blood pressure in preeclampsia. The purpose of this cross-sectional study is to evaluate the serum magnesium level in preeclamptic women. For this study 50 preeclamptic patients, with age range 20 to 40 years having gestational age range from 20 to 40 weeks and 50 age and gestational age matched normotensive pregnant women having no proteinuria were enrolled. Serum magnesium was measured by colorimetric method. The mean(±SD) age and mean(±SD) gestational age of preeclampsia was not significantly different from those of normotensive pregnant women (p=0.203 and p=0.251 respectively). The mean(±SD) body mass index of the preeclamptic patients was significantly higher compared to that of normotensive pregnant women (p<0.001). The mean(±SD) serum magnesium level was 3.37±2.05 mg/dl in preeclamptic group and 2.87±1.38 mg/dl in normal pregnant women; the level did not differ significantly between the subject of preeclampsia and normal pregnant women (p=0.153). Findings of this study suggest that serum magnesium has no association with preeclampsia.Bangladesh J Med Biochem 2017; 10(1): 10-15

Pre-eclampsia is the most common medical complication of pregnancy associated with increased maternal and infant mortality and morbidity. Reduced serum calcium level are found associated with elevated blood pressure in preeclampsia. To evaluate serum calcium level in pre-eclamptic women. This cross sectional study was carried out in among 50 preeclamptic patients, aged 20 to 40 years, and gestational age ranges from 20 to 40 weeks and 50 age and gestational age matched normotensive pregnant women having no proteinuria. Serum calcium was measured by Colorimetric method. The mean age and mean gestational age of pre-eclampsia was not significantly different from those of normotensive pregnant women (p=0.203 and p=0.251 respectively). The mean body mass indexes of the test patients were significantly different from those of normotensive pregnant women (p<0.001). The mean serum calcium level was 7.27 ± 3.01 mg/dl in pre-eclampsia and 7.25 ± 2.59 mg/dl in normal pregnant women; did not differ significantly between the subjects of pre-eclampsia and normal pregnant women (p=0.963). Serum calcium has no association in occurrence of preeclampsia.

2) late onset preeclampsia (after 34 wks gestation) 5 .Preeclampsia creates a functional derangement of multiple organ system. Complications of preeclampsia include eclampsia, placental abruption, ascities, hepatic infarction and rupture, intra-abdominal bleeding, pulmonary edema and acute renal failure. Twenty percent (20%) of women with severe preeclampsia develops HELLP syndrome (hemolysis, elevated liver enzymes, low platelets) and the same percentage (20%) among HELLP syndrome develops disseminated intravascular coagulation (DIC). Complications affecting the developing fetus include intrauterine growth retardation, prematurity, oligohydramnios, bronchopulmonary dysplasia and increased risk of perinatal death 2 . During normal pregnancy profound changes occur in the coagulation and fibrinolytic system of the mother causing a hypercoagulable state. In preeclampsia there is a distinct possibility of accentuation of this hypercoagulable state of pregnancy 4 .Numerous studies observed coagulation abnormalities in preeclampsia. The level of anticoagulants such as antithrombin III, protein C and protein S are decreased in these groups. The clotting factors such as factor VIII and von Willebrand factors are elevated in preeclampsia. There is also increase in plasminogen activator inhibitor type 1(PAI-1) in preeclampsia. So preeclampsia is a highly thrombotic and procoagulant state 1 .Fibrinogen is the primary blood clotting factor. Fibrin clot is formed from fibrinogen. Fibrinogen plays a vital role in the process of inflammation, atherogenesis and thrombogenesis. Fibrinogen is a cofactor in platelet activation and may directly contribute to platelet plaque

Introduction: The purpose of giving the TT vaccine to women of childbearing age and to pregnant women is to protect them from tetanus and to protect their newborn infants against neonatal tetanus. Materials and Methods: A descriptive cross-sectional study was done on January, 2017 to find out the TTvaccination status of students of Khulna Government Pioneer Girls College, Khulna. During scheduled time period. Data were collected from 100 respondents selected by purposive type of convenient sampling by face to face interview using a prepared mixed type of questionnaire. Results: Among total respondent’s majority 36(36%) were belonged to 17-19 years of age group. People of our country nowadays more aware of TT vaccination as 97 (97%) of our total respondents had knowledge about TT vaccination. Achievement in TT vaccination coverage has been impressive throughout the country in recent years. It has also been reflected in our study, we had 84(84%) coverage and 55 (42%) of our respondents had completed their vaccination (5doses). Establishment and improvement of infrastructure of government health organizations 70(83.33%) of our study population received vaccination in government organization. Acceptance of TT vaccination has increased to a satisfactory level. In our study TT vaccination coverage was maximum (85.51%) in upper class and only (71.43%) in lower class respondents. Conclusion: Despite high knowledge, completion of recommended doses of TT vaccine was not guaranteed due to stock-outs coupled with detrimental cultural and religious beliefs.That is why large scale study is needed to find out TT coverage among women of reproductive age group (15-49 years) of Bangladesh which can ensure the real scenario as well as factors related to this. Medicine Today 2019 Vol.31(2): 117-119

Introduction: There are many Hypertensive disorders in pregnancy like preeclampsia, eclampsia etc. Pre-eclampsia is the most common medical complication of pregnancy associated with increased maternal and infant mortality and morbidity. Some studies have implicated that low serum calcium levels may have a role in pre-eclampsia but other studies failed to find relation between low levels of these trace elements and pre-eclampsia. Materials and Methods: This cross sectional study was carried out in the Department of Biochemistry, Sylhet MAG Osmani Medical College in collaboration with the Department of Obstetrics and Gynaecology, Sylhet MAG Osmani Medical College Hospital during the period from January 2016 to December 2016. This Study was occured in among 31 pre-eclampsia patients, aged 20 to 40 years, and gestational age ranges from 20 to 40 weeks and 31 age matched normotensive non-pregnant women having no proteinuria. Serum magnesium was measured by Colorimetric method. Results: The mean serum magnesium level was 3.24 (±1.42) mg/dl in pre–eclampsia and was 3.30 (±1.5) mg/dl in normal women. The mean serum magnesium level did not differ significantly between the subjects of pre–eclampsia and normal women (t=0; p<.05). Conclusion: The means of both data sets are equal. So we can conclude that there is no significant difference between them. Medicine Today 2021 Vol.33(1): 58-60