Objective Contemporary clinical guidelines endorsed that glycemic control is the ultimate goal in the management patients with diabetes. The aim of this study was to assess the prevalence of glycemic control and to identify predictors of poor glycemic control in patients with type 2 diabetes (T2D). A cross-sectional study was conducted among systematically selected 357 diabetic patients. Data were collected through direct patients’ interviews and medical chart review. Binary logistic regression analyses were performed and analyzed using SPSS version 22.0. Results Participants’ mean age was (± SD) 56.1 ± 11.6 years. Nearly four in five (77.9%) of the participants had comorbidities, mainly of hypertension, and 60.2% had diabetic complications, mainly diabetes neuropathy. Poor glycemic control was found in 68.3% of the participants with a mean (± SD) FBG of 174.1 ± 48.9 mg/dL. Being female gender, having greater body mass index and low medication adherence was significantly associated with poor glycemic control. In conclusion, the overall aspects of glycemic control level of patients were far from the standards. Being female, greater body mass index and poor medication adherence were predictors of poor glycemic control. In response to this finding, an aggressive intervention that targets in improving the glycemic control is required. Electronic supplementary material The online version of this article (10.1186/s13104-019-4248-6) contains supplementary material, which is available to authorized users.
International Union Against Tuberculosis and Lung DiseaseHealth solutions for the poor C hronic non-communicable diseases have emerged as the next twenty-first century global epidemic and have already become the leading causes of death and disability worldwide. 1 Among these, the global burden of diabetes mellitus (DM) is immense. In 2013, an estimated 382 million people were living globally with DM, with numbers expected to rise to 592 million by 2030. 2 Most of these persons have type 2 DM, and given the association between DM and unhealthy lifestyles, such as poor diet and physical inactivity, there are more people with DM in urban than in rural areas; this divide is estimated to reach 314 million and 143 million, respectively, in 2030. In 2013, DM-related complications were a major cause of disability and reduced quality of life, and an estimated 5 million people aged 20-79 years worldwide died prematurely from the disease. 2 Although Asia is the epicentre of the DM pandemic, there is an increasing burden of disease in sub-Saharan African countries. 3 A systematic review of studies in Ethiopia from 1970 to 2011 suggested that DM prevalence in the country was about 2%, rising to 5% in persons aged 40 years in certain settings. 4 A more recent nationwide World Health Organization (WHO) STEPS survey among 2153 persons in Ethiopia found the DM prevalence to be 6.5%. 5 It is therefore important to monitor and anticipate the growing burden of DM and related complications, together with treatment outcomes, for the purpose of resource planning (i.e., the human and material resources needed to diagnose, treat and manage this disease) and to inform future control and management strategies.A previous study in two specialised hospitals in Addis Ababa documented the trend in DM admissions between 2005 and 2009, noting that admissions increased from 51 per annum to 245 over this period. 6 Up-to-date information on the indications for hospital admission, the types of DM, existing complications and hospital outcomes is important, as this will help policy makers and health care staff better understand the DM burden and associated comorbidities. In Ethiopia, where there are no community-level studies on the burden of DM, hospital data serve as a useful proxy.The aim of the present study was therefore to document indications for admission, complications and hospital outcomes of patients with DM admitted to the largest referral hospital (in Addis Ababa, Ethiopia), and compare findings between patients with type 1 and type 2 DM. Specific objectives for patients stratified by type of DM were to describe 1) demographic characteristics and indications for hospital admission, 2) existing complications and comorbidities, and 3) hospital outcomes. METHODS Study designThis was a retrospective descriptive study using medical files. SettingGeneral setting Ethiopia, located in the Horn of Africa, is the third most populated country in sub-Saharan Africa, with 80 million inhabitants, of whom 80% live in rural areas. The country has arou...
BackgroundPatients with diabetes are at high risk of drug therapy problems (DTPs), as they are receiving multiple medications. To date, studies regarding DTPs in patients with diabetes in Ethiopia are limited. The aim of this study was to assess prevalence of DTPs, medication adherence and treatment satisfaction of patients with diabetes at Tikur Anbessa Specialized Hospital (TASH).MethodA cross-sectional study was conducted on randomly selected 418 participants who fulfilled the inclusion criteria. Data were collected using structured questionnaire and patients’ chart review. Cipolle’s classification system was used to determine DTPs. Modified Morisky’s Adherence Scale (MMAS-8) was used to measure patients’ adherence to their medication. Treatment Satisfaction with Medicines Questionnaire (SATMED-Q) patient satisfaction assessment questionnaire was used to assess patients’ treatment satisfaction.ResultsA total of 207 DTPs in 177 (42.3%) of participants were identified. Commonly identified DTPs were dosage too low (58, 28.0%), ineffective drug therapy (54, 26.1%), and need additional drug therapy (52, 25.1%). Factors associated with DTPs were female gender (Adjusted Odds Ratio [AOR] = 2.31,95% CI:1.30–4.12); ≥3comorbidities (AOR = 3.61, 95% CI:1.19–10.96); ever married (AOR = 2.58,95% CI:1.23–5.48); type 2 diabetes (AOR = 5.62, 95% CI:1.21–26.04); non-adherence (AOR = 5.26,95% CI:2.51–11.04) and residence out of Addis Ababa (AOR = 0.30, 95% CI:0.12–0.73). Twenty four percent of participants were non-adherent to their drug therapies. Factors associated with non-adherence were diabetes complications (AOR = 2.00, 95% CI: 1.2–3.32), the female gender (AOR = 1.67, 95%CI: 1.01–2.8) and level of education (AOR = 0.42, 95%CI: 0.18–0.96). Eighty one percent of participants were satisfied with the current treatment.ConclusionA significant proportion of patients were satisfied with their treatment and a quarter of the study participants were non-adherent to their medications at TASH diabetic clinic. However, DTPs were considerably higher among the study participants. Hence, future interventions targeting prevention and resolution of DTPs deemed to be necessary.
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