Among the measures adopted by several governments during the COVID-19 pandemic to inhibit agglomeration and consequently the contagion of a high number of people, is the closing of gyms and other spaces for the practice of resisted physical exercise, which can cause detraining both athletes as non-athletes. Thus, the purpose of this communication was to present the possibility of using elastic resistance training in order to minimize the effects of interruptions in training conducted before the isolation period. In this sense, it can be verified that, since performed in a way that respects the principles of resistance training, elastic resistance training is safe and efficient for use regardless of age and gender.

Influence of irisin release induced by physical exercise on Alzheimer treatment: a review ABSTRACT Alzheimer's disease (AD) causes progressive cerebral atrophy and memory loss, leading to dementia, disability, and death. Irisin is part of myocins, which are substances secreted by the muscle due to contraction. This work aimed to investigate the effects of irisin on slowing the progression of Alzheimer's disease. This research was a qualitative exploratory study of bibliographic character and theoretical survey based on scientific articles from the last ten years on the implications of irisin in the treatment of Alzheimer's disease. The papers found an interaction between irisin and the protein that produces the toxic substance that characterizes Alzheimer's disease. It has been shown that RESUMO A doença de Alzheimer (DA) causa atrofia cerebral progressiva e perda de memória, levando a demência, incapacidade e morte. A irisina faz parte do grupo de miocinas, que são substâncias secretadas pelo músculo em consequência da contração. O objetivo deste trabalho foi investigar quais são os efeitos da irisina para retardar a progressão da doença de Alzheimer. Esta pesquisa tratou-se de um estudo qualitativo exploratório, de caráter bibliográfico e de levantamento teórico com base em artigos científicos dos últimos 10 anos sobre as implicações da irisina no tratamento da doença de Alzheimer. Os artigos encontrados mostraram que há interação entre a irisina com a proteína produtora da substância tóxica que caracteriza a doença de Alzheimer. Foi mostrado que os cérebros com DA têm uma quantidade menor de irisina e que esta substância apresenta um potencial protetivo aos neurônios evitando que a proteína amiloide-beta se ligue a eles, prevenindo a perda neuronal. A irisina também foi relacionada com um importante indicador de saúde cerebral, o BDNF, mostrando que a quantidade de ambos é diretamente proporcional. Além disso, pesquisas realizadas com idosos mostraram que os resultados dos testes cognitivos foram melhores com aqueles que apresentaram um nível maior de irisina no líquido cefalorraquidiano. Concluiu-se que a FNDC5/Irisina tem um grande potencial para o tratamento de pessoas com a doença de Alzheimer, que o exercício físico é algo que pode ajudar no tratamento da doença, porém há a necessidade de mais estudos que investiguem diretamente os efeitos da irisina no tratamento da DA.

According to the World Health Organization, even during the quarantine of the COVID-19 pandemic, it is necessary for people to remain active in order to minimize the damage to physical and mental health caused by social isolation. However, not all models of physical training that have been seen during these past few days are beneficial to all individuals who perform them. Therefore, the purpose of this communication is to analyze the positive and negative points of the main models of physical exercises used in training done at home, seeking to corroborate with better proposals that are more effective for the performers.

A clinical case is presented. The reason for admission was for behavioral disturbances and agitation piscomotriz episode in the street: she had gone to a library to “denounce” the police for entering the subway without paying several times. The patient was very distraught because she was heavily guarded (someone had tapped her phone, entered her house, changed objects place, she was chased down the street…). In the psychopathological examination revealed the sphere of language, her speech was fluid, with pressured speech, full of details, with loss of thread and highlighted the presence of neologisms and grammatical errors (changes of subject and predicate…) and changes some letters by others in the same word. She often used sayings incorrectly and, when you are exploring about this fact, objectively presenting alteration in abstract thinking. In addition, it presents self-references on television. The diagnostic impression was chronic psychotic process of years of evolution. In this case, it was decided to administer intramuscular antipsychotic treatment because she was not aware of the disease but presenting good tolerability profile because, otherwise, leave the track and also a good social functioning was sought. Currently, she continues in mental health, she has not reported new crisis and a progressive scan objective improvement in the organization of thought and speech, leaving the psychotic symptoms.Disclosure of interestThe authors have not supplied their declaration of competing interest.