Wastage of all blood components, including RBCs, platelets (PLT), and plasma, is an important issue for hospitals worldwide. Waste is not limited to blood products and is present throughout the health care system.1 Studies of systemic waste have examined the importance of workflows in the health care environment.2 and have focused on min im iz in g operational sources of waste when issuing a variety of medications. In many of these studies, relatively simple interventions resulted in marked reductions in wastage. The present study is designed to analyze the reason for the extent and wastage of whole blood and different blood components. By that we can minimize or prevent the wastage of blood and supply adequate amount of blood components to the patients whenever required for saving the lives. Aims and Objectives: The basic aim of this study is To understand the extent of wastage of different blood components. To identify various causes of wastage Materials and Methods: This is a retrospective and prospective study carried out in A D Gorwala Blood Bank, Shri Krishna Hospital, Karamsad after HREC approval, from 1st January 2015 to 31st December 2015. All the components, like whole blood unit (WBU), Red Cell Concentrate (RCC), Platelet Concentrate (PC),Fresh Frozen Plasma (FFP),Cryoprecipitate (CP), and Cryopoor plasma (CPP) except Single donor plate lete (SDP), wasted during this study period due to any reasons were included in the study. Statistical Analysis: It is an observational study so descriptive statistics is applied. Results: Age, gender, and blood group wastage of blood components were analysed and it was found that most common wastage was found in male donor between 18 to 30 years of a ge, in " B" Positive blood group. In this study also reason for wastage of different blood components and components wise wastage reason also analysed. Most common component wasted was platelet concentrate due to short shelf life and due to 1st run reactivity in TTI testing. Conclusion: The most component wasted was platelet concentrate due to its short expiry life followed by TTI (transfusion transmitted infection) reactivity after 1st run of ELISA. To avoid wastage of blood components continued training of staff, involved in counseling of donor, phlebotomy and TTI testing along with inventory control regarding the stock position and requirement of different blood group is necessary.  Regular audit of transfusion of blood component by transfusion committee helps in reduction of blood wastage and also promotes its rational use.

Hairy cell leukemia (HCL) is a rare chronic B-cell leukemia accounting for 2% of all the leukemias and occurs more frequently in the elderly males. The etiology is unknown but possible relationships to radiation exposure, exposure to benzene, to farm animals and to commercial herbicides and pesticides have been identified. Familial predisposition among first degree relatives has been noted. It is characterized by distinctive cytoplasmic “hair like” projections on the cell surface of lymphoid cells, pancytopenia and splenomegaly. We report a rare case of 29 year old female, farm labourer presenting with fever, fatigue and weakness for 1 month. On examination the patient had hepatomegaly, massive splenomegaly and inguinal lymphadenopathy. After peripheral smear examination diagnosis of HCL was made which was confirmed by bone marrow aspiration examination, bone marrow biopsy and immunohistochemistry (IHC). [Int J Res Med Sci 2013; 1(4.000): 604-606

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