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This paper refers to the Overall Heat Transfer Coefficient of Nano Fluids (OHTCNF) in heat exchangers and the relevant effective parameters. An improvement in Heat Transfer (HT) and OHTCNF containing nanoaluminum oxide with ca. 20 nm particle size and particular volume fraction in the range of 0.001-0.002 has been reported. The effects of temperature and concentration of nanoparticles on HT variation as well as Overall Heat Transfer Coefficient (OHTC) in a countercurrent double tube heat exchanger with turbulent flow have been studied. The experimental results show a remarkable 8%–10% rise in the mean HT and the OHTC. Accordingly, with an increase in the processing temperature and/or particle concentration the OHTC was observed to increase.