Objective: To analyze factors related with neurologic deficits to patients with ischemic stroke in Seruni Central of Ulin Hospital Banjarmasin. Methods: Analytical observational study with cross sectional approach, population and sample were outpatient ischemic stroke in Ulin Hospital. Taken sampling technique with accidental sampling in 13 March-30 April 2017 amounted 30 people. Data collection used observation sheets, used two statistical analyzes is Mann Whitney Test and Pearson Correlation Test on the degree of confidence 95% Result: Respondents with right hemisphere lesion 13 people (43.3%), left hemisphere lesion 17 people (56.7%). The mean lesion area is 3.54 cm³, the minimum lesion area is 0.015 cm³, the maximum lesion area is 13.60 cm³. Neurologic deficit (NIHSS 48 hours) was obtained on mean score 10.72, minimum NIHSS score 3 and maximum NIHSS score 29. Conclusion: There is corrrelation between the location of the lesion and the neurologic deficit in ischemic stroke patients in Ulin Hospital Banjarmasin (p=0,000 ≤ 0,05). There is correlation between the extent of the lesion and the neurologic deficit in ischemic stroke patients in Ulin Hospital Banjarmasin (r= 0,910; p= 0,000 ≤ 0,05).