In this work, the crude MeOH extract of fruits of Dipterocarpus retusus Blume (Dipterocarpaceae) growing in Vietnam was prepared and studied. Five compounds: ε-viniferin, paucifloroside, ursolic acid, quercetin, and (+)-catechin, was isolated. The structures of these compounds were elucidated by spectroscopic methods. The extracts from fruits of D. retusus Blume by metanol and its some isolated stilbene compounds were evaluated for anti-inflammatory effect activities.
The first study on chemical constituents and biological activities of fruits of Dipterocarpus retusus Blume (Dipterocarpaceae.) growing in Vietnam was reported. Column chromatography of the ethyl acetate extract led to the isolation of five compounds: eleutherol (1), 3, 5, 4' - trihydroxy - trans - stilbene (2), polydatin (3) and β-sitosterol (4), β-sitosterol-3-O-β-D-glucopyranoside (5). Their structures were elucidated based on the NMR spectroscopic methods and comparison with literature date. The extracts from fruits of D. retusus Blume by n-hexane, ethyl acetate and butanol, consecutively, were evaluated for antioxidative and cytotoxic activities.
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