The genus Glycyrrhiza (Fabaceae), with over 30 species, includes plants with abundant medicinal properties that have been prevalently used for a long time in traditional medicine. Today, along with the rapid development of modern medicine, this traditional medicine still plays an important role in the research and development of many new drugs. This report emphasized the contribution of some major components of Cam thao (Licorice), one of the species with multifaceted pharmacological effects and used to produce new drugs. Numerous studies have discovered that Licorice contains important substances that affect the physiological activities of living organisms, such as liquirtin, rhamnoliquirilin, liquiritigenin, prenyllicoflavone A, glucoliquiritin apioside, 1metho-xyphaseolin, shinpterocarpine, shinflavanone, licopyranocoumarin, isoflavone, licoarylcoumarin, glycyrrhizin, and manifold components. In this review, the most recent research results within the last 5 years on the pharmacological effects of Licorice are systemized according to the role of Licorice on nervous, respiratory, digestive, immune, reproductive systems (both male and female) and metabolism. It is predicted that Licorice (Fabaceae) will certainly continue to be the subject of manifold scientific works in the future. The effects that have been interesting in the scientific community recently are: oxidation prevention, memory impairment prevention, weight loss, reproductive function improvement in obese men, and immune system function enhancement in many types of cancer. In addition, previous and ongoing studies have shown that Glycyrrhizin, an active ingredient found in Licorice, is effective against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) because of its antiviral activity. As a result, Licorice can be considered a promising future herbal medicine vital to individual and community health.
Background: Obesity is a global health issue caused by consuming too much energy compared to the body's needs, which negatively impacts almost every organ of the body. As a result, generating an experimental obesity model is critical for researching new drugs to improve obesity and its consequences. Objectives: Generating obesity model of male mice over a 6-week period of feeding by a high-fat diet. Materials and methods: In this experimental research, 24 male mice (Swiss albino) of 3,5 weeks old were divided into 2 groups, each containing 12 mice: control group fed by a normal-fat diet (NFD) and obesity group fed by a high-fat diet (HFD) in a period of 6 weeks. Evaluation was conducted at the beginning of research, every 7 days and at the end of the study. Results: The mean of body weight, weight gain, body length, body mass index (BMI), chest and waist circumference of HFD group had a statistically significant difference from the end of week 2. The morphological difference was more remarkable at week 3 (p<0.001). After 6 weeks of study, the weight gain rate of HFD group was 131.32% higher than the NFD group. It was also noticeable that the weight of omental fat and renal fat (both sides) in the HFD group was significantly higher than that of the NFD group (p<0,001). Conclusions: Research has successfully generated an obesity model in male mice after a period of 6 weeks by a HFD (640Kcal/100g, 52-53% lipid).
Background: The menstrual cycle is a health indicator in women. The change in health makes female students feel less confident in communicating, studying, and living. Therefore, the study on the characteristics of the menstrual cycle in female medical students brings many practical meanings by figuring conclusions and solutions to improve both physiological and mental discomforts for women during menstruation. Objectives: Can Tho University of Medicine and Pharmacy (CTUMP) 3rd year medical students were studied for the characteristics, the abnormalities of the menstrual cycle, and the premenstrual syndrome. Materials and methods: The design of a cross-sectional descriptive study with analysis by direct interview method was conducted on 126 female 3rd year medical students at CTUMP. Results: Long menstrual cycle time accounted for 38.1% of subjects, while short menstrual cycle time accounted for 0.8%. The study also found that the average menstrual period was 5.00±1.34 days. The premenstrual syndrome was observed in 47.3% of students, with abdominal pain and low back pain accounted for the highest rate (63.5%), and headache accounted for the lowest rate (9.5%). Menorrhagia had a low prevalence (7.1%), whereas menstrual cramp was much more common (60.3%). Conclusions: Long menstrual cycles occurred at a high rate among medical students. Abdominal pain and low back pain were the most common symptoms before menstruation. Menstrual cramp was the most common abnormality of the menstrual cycle among CTUMP female medical students.
Background: Coronavirus Disease 2019 (COVID-19) pandemic got extremely complicated in 2021, appeared many new strains of viruses with high infectivity. So, knowledge and manipulation were important for protecting students against infection in COVID-19 sampling. Objectives: The study surveyed knowledge of students’ infection control when participating in COVID-19 test sampling in the community. Materials and methods: A cross-sectional descriptive study was conducted on 195 volunteer students of Can Tho University of Medicine and Pharmacy (CTUMP). A series of 11 questions were also used to interview the participants. Results: The proportion of female volunteers who participated in the research was 52.8%, higher than male volunteers (47.2%). Students in the 45th cohort participated in research with the highest quantity (43.6%) and the lowest in the 42nd cohort (0.5%). The research had the largest number of general medical students participating (69.2%). The results showed that the knowledge of regular hand washing, removing gloves, removing N95 masks, and the time of disinfection spray with median points equal to the maximum point. The median overall knowledge score for the principle of removing Personal Protective Equipment (PPE) was 50%, compared to the maximum point of 100%. Only 24.6% of students got maximum scores in the knowledge of minimum safe distance, whereas 98.5% achieved maximum scores in the knowledge of COVID-19 sample collection skills. Conclusions: Students who took part in COVID-19 community sampling had a good understanding of most research topics. However, the principle of removing PPE was not well-understood.
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