Introduction: Molar pregnancies represent a significant burden of disease on the spectrum of gestational trophoblastic diseases. Vaginal bleeding being the most common occasionally, molar pregnancy is complicated by hyperthyroidism, which may require treatment. Aims: To determine thyroid function test and association of hyperthyroidism among the cases of molar pregnancy. Methods: This is a hospital-based cross-sectional study conducted in the department of Obstetrics and Gynecology, Nepalgunj Medical College and Teaching Hospital, Kohalpur. Sixty cases of molar pregnancy were included during the study period from February 2020 to January 2021.Patients having history of known thyroid disorders were excluded. Results: Prevalence of molar pregnancy in our study was 5.4 per thousand pregnancies in our hospital. Molar pregnancy and hyperthyroidism, both were common in the age group of 21-35 years. Hyperthyroidism was present in 10% patients. Enlarged thyroid was seen in 3.3%, tremor was present in 3.3%, and palpitation in 21.5%. Five (8.3%) patients with hyperthyroidism were underweight. Majority of patients with hyperthyroidism, beta humanchorionic gonadotrophhin level was more than three lakhs and it was mostly associated with complete hydatidiform mole compared to partial hydatidiform mole. Thyroid storm was not experienced in any of the patients. Conclusion: The rate of molar pregnancy is high. Hyperthyroidism in molar pregnancy is not uncommon. High levels of human chorionic gonadotropin, complete hydatiform mole are directly associated with hyperthyroidism. Awareness of this condition is important for diagnosis and treatment to prevent life threatening complications.

Introduction: Anemia in pregnancy is a public health problem of developing countries and has a significant impact on the health of mother and fetus. It is one of the leading cause responsible for maternal and perinatal morbidity and mortality. Aims: To find out the severity of anemia in pregnancy and its maternal and perinatal outcome. Methods: A prospective randomized case control study undertaken in the Department of Obstetrics and Gynecology, Nepalgunj Medical College, Kolhapur from September 2019 to August 2020. Total of 200 study subjects were enrolled, cases and control were 100 each, with cut off for anemia as 11gm/dl. Results: Out of 100 cases of anemia, 58 were mildly anemic (Hemoglobin: 10-10.9), 23 moderately (7-10) and 21 severely anemic (<7gm/dl). Anemic cases were found to have higher incidence of preterm birth (8%), postpartum hemorrhage (5%), and maternal morbidity (19%) than in non-anemic controls. Adverse fetal outcome in the form of preterm birth (8%), Intrauterine Growth Restriction (14%), Still birth (3%), Early neonatal death (4%), Low birth weight babies (22%), neonatal morbidity (17.5%) was more in anemic  group than non-anemic controls. Conclusion: Anemia in pregnancy has adverse effects on the mother and fetus. It is important to diagnose and treat anemia in pregnancy to ensure optimal health of mother and newborn.

An outbreak of novel coronavirus pneumonia occurred worldwide since December 2019, which had been named COVID-19 subsequently. It is extremely transmissive that infection in pregnant women were unavoidable. The delivery process will produce large amount of contaminated media, leaving a challenge for medical personnel to ensure both the safety of the mother and infant and good self-protection. Here, we report a 27 year woman had reverse transcription polymerase chain reaction-confirmed COVID-19 at 37 weeks 2 days of gestation. An emergency caesarean section at 38 weeks 2 days of gestation under spinal anaesthesia was performed for oligohydramnios with scar tenderness with strict protection for all personnel.